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EGFR-IN-159

EGFR-IN-159 (compound 12), a dihydropyrimidine, is a potent EGFR inhibitor with an IC50 value of 29.00 nM. EGFR-IN-159 exhibits dose-dependent inhibition against EGFR and HER2. EGFR-IN-159 shows cytotoxicity against MCF-7 breast cancer cells and Vero cells with IC50 values of 16.07 μg/mL and 35.98 μg/mL, respectively. EGFR-IN-159 has no BBB permeation. EGFR-IN-159 shows appreciable anti-cancer activity.

For research use only. We do not sell to patients.

  • CAS No.: 2055746-08-0
  • Formula: C21H23N3O5
  • Molecular Weight:397.42
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • EGFR-IN-159 Chemical Structure
    EGFR-IN-159 Chemical Structure
CAS No.: 2055746-08-0
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  • EGFR-IN-159 Chemical Structure
    EGFR-IN-159 Chemical Structure
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  • EGFR-IN-159