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F. oxysporum

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (1) Bacterial (3) Drug Derivative (1) Drug Intermediate (2) Fungal (13) HIV (1) Reactive Oxygen Species (ROS) (1) Reference Standards (1)
By Research Areas:	Cancer (1) Infection (13)

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Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y0603

3-Hydroxyacetophenone m-Hydroxyacetophenone	Drug Intermediate Fungal	Others
3-Hydroxyacetophenone (m-Hydroxyacetophenone) is a hydroxy-substituted alkyl phenyl ketone and also a plant defensin in carnations. 3-Hydroxyacetophenone has antifusarium activity. In addition, 3-Hydroxyacetophenone can be used to synthesize Rivastigmine (HY-17368) .

HY-N8722

Datiscetin	Fungal	Infection
Datiscetin (compound 5) is a natural compound isolated from the cultivar “Roland”, and shows fungitoxic activity towards *F. oxysporum* f. sp. dianthi.** .

HY-N8420

Thalifoline	Fungal	Infection Cancer
Thalifoline is an isoquinoline alkaloid. Thalifoline exerts cytotoxic effects on cancer cells. Thalifoline inhibits the growth of Fusarium oxysporum f. sp. lycopersici. Thalifoline can be used in research related to lung adenocarcinoma, colon cancer, oral epidermoid carcinoma, and fungal infections .

HY-129316

(S)-Dihydroaeruginoic acid CGP 52547	Antibiotic Fungal Bacterial	Infection
(S)-Dihydroaeruginoic acid is an antibiotic originally isolated from P. fluorescens. It has antimicrobial activity in a disc assay against R. solani, P. ultimum, B. cinera, S. rolfsii, C. gloeosporioide, F. oxysporum, and S. tritici fungi as well as B. subtilis, E. herbicola, and S. albus bacteria when used at a concentration of 200 μg/disc.

HY-P11176

Coccinin	Fungal HIV	Infection
Coccinin is an antifungal peptide. Coccinin can be purified from the seeds of large scarlet runner beans. Coccinin inhibits HIV-1 reverse transcriptase. Coccinin shows antifungal activity against M. arachidicola, F. oxysporum, P. piricola, B. cinerea, C. comatus and R. solani, with IC₅₀s of 75, 81, 89, 109, 122 and 134 μM, respectively .

HY-N7307

Pachybasin	Bacterial	Infection
Pachybasin is a major metabolite from culture broth of endophytic coelomyceteous AFKR-18 fungus. Pachybasin showes antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively .

HY-155761

Antifungal agent 71	Fungal	Infection
Antifungal agent 71 (compound 6r) is a trifluoromethyl pyrimidine derivative with antifungal activity. Antifungal agent 71 exhibits good in vitro antifungal activity against F. oxysporum, with the EC₅₀ value of 3.61 μg/mL .

HY-155658

Antifungal agent 62	Fungal	Infection
Antifungal agent 62 (Compound 3a) is a fungicidal agent with excellent fungicidal activities against Fusarium oxysporum* f.sp. cucumerinum*. Antifungal agent 62 can be used for antiviral and fungicidal research .

HY-132968

Antifungal agent 20	Fungal	Infection
Antifungal agent 20 exhibits remarkable antifungal activity against Colletotrichum gloeosprioides, Rhizoctonia solani, Phytophthora nicotianae var. nicotianae, Diplodia pinea, Colletotrichum acutatum, and Fusarium oxysporum* f. sp. niveum*.

HY-155669

Antifungal agent 64	Fungal	Infection
Antifungal agent 64 (Compound 5c) is a fungicidal agent with excellent fungicidal activities against Fusarium oxysporum* f.sp. cucumerinum*. Antifungal agent 64 can be used for antiviral and fungicidal research .

HY-155670

Antifungal agent 65	Fungal	Infection
Antifungal agent 65 (Compound 5d) is a fungicidal agent with excellent fungicidal activities against Fusarium oxysporum* f.sp. cucumerinum*. Antifungal agent 65 can be used for antiviral and fungicidal research .

HY-155660

Antifungal agent 63	Fungal	Infection
Antifungal agent 63 (Compound 3i) is a fungicidal agent with excellent fungicidal activities against Fusarium oxysporum* f.sp. cucumerinum*. Antifungal agent 63 can be used for antiviral and fungicidal research .

HY-183295

Antifungal agent 160	Fungal Reactive Oxygen Species (ROS)	Infection
Antifungal agent 160 is a cytochrome bc₁ complex inhibitor with activity against Alternaria solani, Gibberella zeae, Colletotrichum gloeosporioides, and Fusarium oxysporum f. sp. melonis. Antifungal agent 160 impairs ATP synthesis, suppresses ATPase activity, induces ROS bursts, compromises plasma membrane integrity, and suppresses fungal growth. Antifungal agent 160 can be used for the research of fungal infection .

HY-Y0603R

3-Hydroxyacetophenone (Standard)	Drug Intermediate Fungal Reference Standards	Others
3-Hydroxyacetophenone (Standard) is the analytical standard of 3-Hydroxyacetophenone (HY-Y0603). This product is intended for research and analytical applications. 3-Hydroxyacetophenone (m-Hydroxyacetophenone) is a hydroxy-substituted alkyl phenyl ketone and also a plant defensin in carnations. 3-Hydroxyacetophenone has antifusarium activity. In addition, 3-Hydroxyacetophenone can be used to synthesize Rivastigmine (HY-17368) .

HY-171699

Antibacterial agent 339	Bacterial	Infection
Antibacterial agent 339 is an antibacterial agent. Antibacterial agent 339 inhibits the growth of Fusarium oxysporum f.sp.cubense Race 4 with a MIC of 50.5 μM. Antibacterial agent 339 shows low toxicity in mice. FLT3-IN-30 can be used for the research of banana wilt .

HY-W016983

3-Phenylphenol	Drug Derivative	Others
3-Phenylphenol is a secondary metabolite. 3-Phenylphenol can induce the hbp gene cluster in Pseudomonas sp. strain P1B16. 3-Phenylphenol can bind to the Sge1 transcription factor of Fusarium oxysporum f. sp. cubense and disrupt the function of virulence regulators. 3-Phenylphenol can be used in studies related to banana fusarium wilt .

Cat. No.	Product Name	Target	Research Area

HY-P11176

Coccinin	Fungal HIV	Infection
Coccinin is an antifungal peptide. Coccinin can be purified from the seeds of large scarlet runner beans. Coccinin inhibits HIV-1 reverse transcriptase. Coccinin shows antifungal activity against M. arachidicola, F. oxysporum, P. piricola, B. cinerea, C. comatus and R. solani, with IC₅₀s of 75, 81, 89, 109, 122 and 134 μM, respectively .

3-Hydroxyacetophenone m-Hydroxyacetophenone	Monophenols other families Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Phenols Plants Disease Research Fields Source Classification	Drug Intermediate Fungal
3-Hydroxyacetophenone (m-Hydroxyacetophenone) is a hydroxy-substituted alkyl phenyl ketone and also a plant defensin in carnations. 3-Hydroxyacetophenone has antifusarium activity. In addition, 3-Hydroxyacetophenone can be used to synthesize Rivastigmine (HY-17368) .

Datiscetin	Flavonols Flavonoids Plants Caryophyllaceae Source Classification Dianthus caryophyllus L.	Fungal
Datiscetin (compound 5) is a natural compound isolated from the cultivar “Roland”, and shows fungitoxic activity towards *F. oxysporum* f. sp. dianthi.** .

Thalifoline	Infection Alkaloids Structural Classification Monophenols Classification of Application Fields Phenols Plants Isoquinoline Alkaloids Menispermaceae Disease Research Fields Menispermum dauricum Source Classification	Fungal
Thalifoline is an isoquinoline alkaloid. Thalifoline exerts cytotoxic effects on cancer cells. Thalifoline inhibits the growth of Fusarium oxysporum f. sp. lycopersici. Thalifoline can be used in research related to lung adenocarcinoma, colon cancer, oral epidermoid carcinoma, and fungal infections .

Pachybasin	Infection Quinones Monophenols Microorganisms Classification of Application Fields Anthraquinones Phenols Disease Research Fields Source Classification	Bacterial
Pachybasin is a major metabolite from culture broth of endophytic coelomyceteous AFKR-18 fungus. Pachybasin showes antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively .

3-Hydroxyacetophenone (Standard)	Structural Classification Monophenols other families Ketones, Aldehydes, Acids Phenols Plants Source Classification	Drug Intermediate Fungal Reference Standards
3-Hydroxyacetophenone (Standard) is the analytical standard of 3-Hydroxyacetophenone (HY-Y0603). This product is intended for research and analytical applications. 3-Hydroxyacetophenone (m-Hydroxyacetophenone) is a hydroxy-substituted alkyl phenyl ketone and also a plant defensin in carnations. 3-Hydroxyacetophenone has antifusarium activity. In addition, 3-Hydroxyacetophenone can be used to synthesize Rivastigmine (HY-17368) .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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F. oxysporum

Inhibitors & Agonists

Peptides

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Natural
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