141 Results for "

Fc gamma receptor

" in MedChemExpress (MCE) Product Catalog:
Products (141)

141 Results for "Fc gamma receptor" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P70669
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: High affinity immunoglobulin gamma Fc receptor I; Fcgr1; FcRI; CD64; Fc receptor; IgG; high affinity I
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70601
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FcGRT; Major Histocompatibility Complex Class I-Like Fc receptor; Fc gamma receptor And Transporter; Neonatal Crystallizable Fc receptor FcRn Splice Variant 6; Neonatal Fc receptor; Neonatal Crystallizable Fc receptor FcRn Splice Variant 5; FcRn; Neonatal
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70705
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FcGR3A; CD16; Prev. FcGR3; Fc Fragment Of IgG, Low Affinity IIIa, receptor For (CD16); Prev. FcG3; Fc Of IgG Low Affinity IIIa receptor Isoform 2; FcgammaRIIIa; Fc Of IgG Low Affinity IIIa receptor Isoform 1; FcGRIIIA; Immunoglobulin G Fc receptor III; CD
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P7508
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANGPTL4; Peroxisome Proliferator-Activated receptor (PPAR) gamma Induced Angiopoietin-Related Protein; Angiopoietin Like 4; Hepatic Angiopoietin-Related Protein; HFARP; PPARG Angiopoietin Related Protein; PGAR; Fasting-Induced Adipose Factor; ARP4; Angiop
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P99761
CAS No.: 1690307-05-1
Synonyms: XmAb5871

Target:  

CD19 Apoptosis

Research Areas:  

Inflammation/Immunology

Obexelimab (XmAb5871) is a humanized anti-CD19 antibody. Obexelimab works by inhibiting B cell receptor (BCR) mediated calcium influx and promoting the phosphorylation of Fc γ receptor IIb (FcγRIIb), which reduces B cell activation and function, leading to B cell apoptosis. Obexelimab can be used in research for rheumatoid arthritis and systemic lupus erythematosus .
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Cat. No.: HY-P991055
CAS No.: 2649379-96-2
Synonyms: RG-6234; RO-7425781

Target:  

CD3

Research Areas:  

Inflammation/Immunology

Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2 + 1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P990256

Target:  

CTLA-4

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) is a mouse-derived IgG2a κ type antibody inhibitor targeting to mouse CTLA-4/CD152. Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) contains a LALA-PG mutation in the Fc fragment rendering it unable to bind to endogenous Fcγ receptors. Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) can be used for the researches of cancer and immunology, such as colon .
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Cat. No.: HY-P99983

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Mouse IgG1 (D265A) kappa, Isotype Control is a mouse IgG1(D265A)κ isotype control with a D265A mutation and inactivity against mouse Fc gamma receptors (FcγR1, FcγR2, FcγR3, FcγR4) .
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Cat. No.: HY-P990067
CAS No.: 2639688-77-8
Synonyms: ATOR-1017

Target:  

TNF Receptor

Research Areas:  

Cancer

Evunzekibart (ATOR-1017) is an Fc-γ receptor conditional 4-1BB agonist and IgG4-type antibody. Evunzekibart can be used as monotherapy or in combination with anti-PD1 to exert anticancer activity.
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Cat. No.: HY-N16039
CAS No.: 126221-76-9
TAN-1030A is an indolocarbazole alkaloid with macrophage-activating properties. TAN-1030A induces spreading of a murine macrophage cell line, Mm 1, and augmentes the phagocytic activity, Fc gamma receptor expression and β-glucuronidase activity of murine macrophage cell lines, Mm 1 and J774A.1. TAN-1030A can activate macrophage functions in mice .
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Cat. No.: HY-P991074

Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

GMA-161 is a humanized IgG1 antibody that targets Fcγ receptor III (CD16). GMA-161 has the potential for the study of autoimmune disorders. The isotype control for GMA-161 can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P991555

Target:  

TNF Receptor Apoptosis

Research Areas:  

Cancer

XmAb5485 is an Fc-engineered humanized anti-CD40 monoclonal antibody with high affinity to Fc-γ receptors. XmAb5485 induces potent antibody-dependent cell-mediated cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP) against tumor cells. XmAb5485 inhibits proliferation and induces apoptosis of tumor cells. XmAb5485 shows highly cytotoxic against lymphoma, leukemia and multiple myeloma cell lines as well as primary cancer cells .
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Cat. No.: HY-P99911
CAS No.: 1635395-27-5
Synonyms: MEDI-6383
Efizonerimod alfa (MEDI-6383) is a recombinant human OX40L IgG4P Fc fusion protein that assembles into a hexameric structure and exerts potent agonist activity upon binding to OX40. The activity of Efizonerimod alfa is enhanced by Fcγ receptor-mediated aggregation. Efizonerimod alfa binds to OX40 on the surface of activated T cells, induces NF-κB promoter activity in OX40-expressing T cells, and triggers the production of Th1-type cytokines, T cell proliferation, and resistance to regulatory T cell (Treg)-mediated suppression. Efizonerimod alfa enhances the cytolytic activity of tumor-reactive T cells and slows tumor growth in immunodeficient mice. Efizonerimod alfa induces the proliferation of CD4, CD8, and B cells in the peripheral blood of healthy non-human primates. Efizonerimod alfa can be used in the research of advanced solid malignancies and melanoma .
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Cat. No.: HY-P85020
Synonyms: High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD antigen CD64;

Host:  

Mouse

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P85021
Synonyms: High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD antigen CD64;

Host:  

Mouse

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P704866
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FcGR1A; Fc Fragment Of IgG receptor Ia; Fc gamma receptor Ia; IgG Fc receptor I; FcgammaRIa; Fc-gamma RIA; FcGR1; Fc-gamma RI; FcG1; IGFR1; FcgammaRI; Fc-gamma receptor I A1; CD64A; CD64 Antigen; CD64; Fc gamma RI; Fc Fragment Of IgG, High Affinity Ia, Re
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P991848

Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

Anti-CD64 Antibody (10.1) recognizes an epitope on human CD64 (Fc_RI). Fc gamma receptors (Fc_Rs) are membrane-bound proteins which control and mediate communication of IgG antibodies within the immune system. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977) .
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Cat. No.: HY-P70708A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Low affinity immunoglobulin gamma Fc region receptor III; IgG Fc receptor III; Fc-gamma RIII; FcRIII; CD16; Fcgr3
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P78880
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FcGR1A; Fc Fragment Of IgG receptor Ia; Fc gamma receptor Ia; IgG Fc receptor I; FcgammaRIa; Fc-gamma RIA; FcGR1; Fc-gamma RI; FcG1; IGFR1; FcgammaRI; Fc-gamma receptor I A1; CD64A; CD64 Antigen; CD64; Fc gamma RI; Fc Fragment Of IgG, High Affinity Ia, Re
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P76207
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Low affinity immunoglobulin gamma Fc region receptor III; IgG Fc receptor III; Fc-gamma RIII; FcRIII; CD16; Fcgr3
Species:  
Mouse
Source:  
HEK293
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