9 Results for "

Gly-PAB linker

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Gly-PAB linker" in MCE Product Catalog:

Cat. No.: HY-147164
CAS No.: 2632342-16-4
Purity:  99.22%
Target:  

ADC Linkers

Research Areas:  

Cancer

MC-Gly-Gly-Phe-Gly-PAB-PNP is a linker for synthesis anti-human EGFR antibody agent conjugate .
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Cat. No.: HY-177434
CAS No.: 2873366-83-5
Synonyms: Precem-TcT; M 9140
Precemtabart tocentecan (Precem-TcT; M 9140) is an anti-CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5) antibody-drug conjugate (ADC). Precemtabart tocentecan consists of a tumor-specific anti-CEACAM5 monoclonal antibody Precemtabart (HY-P990940), a highly hydrophilic and stable cleavable β-glucuronide linker, and a topoisomerase 1 inhibitor payload Exatecan (HY-13631), and the drug-linker conjugate for ADC is Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179). Precemtabart tocentecan inhibits the growth of CEACAM5-positive cancer cells. Precemtabart tocentecan exhibits significant antitumor activity in CEACAM5-expressing xenograft models. Precemtabart tocentecan can be used for the study of CEACAM5-expressing advanced solid tumors, especially mCRC .
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Cat. No.: HY-136432
CAS No.: 2632342-05-1
Purity:  98.81%
Synonyms: Mc-GGFG-PAB-OH
Target:  

ADC Linkers

Research Areas:  

Cancer

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
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Cat. No.: HY-160885A
Research Areas:  

Others

NH2-Gly-PAB-Exatecan-D-glucuronic acid formic (Compound 8) is an intermediate that reacts with NHS-group-containing molecules to generate the ADC drug-linker conjugate Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179) .
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Cat. No.: HY-132134
CAS No.: 3055607-13-8
Research Areas:  

Cancer

MC-Gly-Gly-Phe-Gly-PAB-MMAE (Compound SMP-81641) is a control targeted linker-agent conjugate. MC-Gly-Gly-Phe-Gly-PAB-MMAE can be used in tumor research .
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Cat. No.: HY-136432A
CAS No.: 2991254-82-9
Purity:  97.48%
Synonyms: Mc-GGFG-PAB-OH TFA
Target:  

ADC Linkers

Research Areas:  

Cancer

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
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Cat. No.: HY-160885
CAS No.: 2763252-31-7
Research Areas:  

Others

NH2-Gly-PAB-Exatecan-D-glucuronic acid (Compound 8) is an intermediate, which reacts with NHS group to form drug-linker conjugate for ADC, Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179) .
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Cat. No.: HY-141146
CAS No.: 2353409-52-4
Target:  

ADC Linkers

Research Areas:  

Cancer

Mal-amido-PEG8-val-gly-PAB-OH is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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Cat. No.: HY-178279
CAS No.: 2928560-28-3
Research Areas:  

Others

Mc-Gly-Gly-Phe-Gly-PAB-pSar11-Exatecan (compound L-D-5) is a toxin-linker compound that can be used for the preparation of antibody-drug conjugates (ADCs) .
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