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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
HeLa-S3 cells
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "HeLa-S3 cells" in MCE Product Catalog:
3
3 Cited Publications
Synonyms: Glucose-conjugated MGMT inhibitor
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O6BTG-octylglucoside is a potent O 6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells.
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Cat. No.: HY-N9172
CAS No.: 476630-49-6
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Cat. No.: HY-N10542
CAS No.: 151923-86-3
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Cat. No.: HY-N10541
CAS No.: 151923-85-2
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Cat. No.: HY-N14947
CAS No.: 190143-30-7
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Cat. No.: HY-N13976
CAS No.: 189871-55-4
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Cat. No.: HY-N15297
CAS No.: 10092-04-3
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Cat. No.: HY-N5186
CAS No.: 154277-21-1
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Cat. No.: HY-N8512
CAS No.: 129277-10-7
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Infection Human Gut Microbiota Metabolites Microorganisms Phenols Polyphenols Endogenous metabolite Disease Research Fields
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Cat. No.: HY-13786
CAS No.: 793035-88-8
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O6BTG-C8-αGlu is an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor with an IC50 of 0.45 μM. At a concentration of 0.1 μM, O6BTG-C8-αGlu can completely inhibit MGMT in HeLaS3 cells. Even when applied chronically at high doses (up to 20 μM), it does not exhibit cytotoxicity. O6BTG-C8-αGlu is suitable for research on MGMT-related cancer diseases .
Cat. No.: HY-101775
CAS No.: 51131-85-2
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9-hydroxyellipticine is an inhibitor of Topo II and RyR, exhibiting high affinity for DNA with a Pka value of 9.8 at pH 7.4. It has antitumor, antioxidant, and catecholamine-releasing activities, with IC50 values of 1.6 μM and 1.2 μM for Hela S-3 and 293T cells, respectively. It also demonstrates anticancer effects in L1210 leukemia mice .
Cat. No.: HY-P10596
CAS No.: 1242413-05-3
Cat. No.: HY-101775AR
CAS No.: 52238-35-4
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Cat. No.: HY-N13975
CAS No.: 189871-53-2
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Cat. No.: HY-N14438
CAS No.: 125108-66-9
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Cat. No.: HY-N14439
CAS No.: 125224-54-6
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Cat. No.: HY-N14440
CAS No.: 134984-98-8
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Cat. No.: HY-181804
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MRS8288 is a ABCG2 and P-glycoprotein inhibitor, with an IC50 of 0.96 μM against ABCG2 and an IC50 of 1.39 μM against P-glycoprotein. MRS8288 inhibits the ATPase activity of ABCG2 and P-glycoprotein, and suppresses ABCG2-mediated substrate transport. MRS8288 is applicable for cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
