10092-04-3
10092-04-3
Chemical Structure
Isotenulin
- CAS No.: 10092-04-3
- Formula:C17H22O5
- Molecular Weight:306.35
SMILES: CC(O[C@H]1[C@]2([C@](C=CC2=O)([H])[C@@H](C[C@@]3([H])[C@@]1([H])[C@H](C(O3)=O)C)C)C)=O
Biological Activity: Isotenulin inhibits the efflux function of P-glycoprotein by stimulation of P-glycoprotein ATPase, thereby overcoming the multidrug resistance (MDR) of cancer cells. Isotenulin exhibits cytotoxicity in multidrug-resistant cancer cell KB-vin and sensitive cancer cell HeLaS3. Isotenulin exhibits synergistic effect with Paclitaxel (HY-B0015), Vinblastine (HY-13780) and Doxorubicin (HY-15142)[1].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Isotenulin | Isotenulin inhibits the efflux function of P-glycoprotein by stimulation of P-glycoprotein ATPase, thereby overcoming the multidrug resistance (MDR) of cancer cells. Isotenulin exhibits cytotoxicity in multidrug-resistant cancer cell KB-vin and sensitive cancer cell HeLaS3. Isotenulin exhibits synergistic effect with Paclitaxel (HY-B0015), Vinblastine (HY-13780) and Doxorubicin (HY-15142). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
