382607-78-5
Chemical Structure
O6BTG-octylglucoside
Synonym(s): Glucose-conjugated MGMT inhibitor
- CAS No.: 382607-78-5
- Formula:C24H34BrN5O7S
- Molecular Weight:616.53
IUPAC Name: (2R,3R,4S,5S,6R)-2-((8-(2-amino-6-((4-bromothiophen-2-yl)methoxy)-9H-purin-9-yl)octyl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChIKey: WAAZBVOGWRQLMB-PUIBNRJISA-N
SMILES: [H][C@]1([C@]([H])(O[C@@](OCCCCCCCCN2C3=C(N=C2)C(OCC4=CC(Br)=CS4)=NC(N)=N3)([C@](O)([C@]1(O)[H])[H])[H])CO)O
Biological Activity: O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
O6BTG-octylglucoside | 95.0% | O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
