7 Results for "

Huperzine A

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Huperzine A" in MCE Product Catalog:

6
(-)-Huperzine A
(-)-Huperzine A
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6 Cited Publications
Cat. No.: HY-17387
CAS No.: 102518-79-6
Synonyms: Huperzine A
Category:  

Alkaloids Neurological Disease Anti-aging Huperziaceae Terpenoids Sesquiterpenes Pyridine Alkaloids Huperzia serrata (Thunb. ex Murray) Trevis. Plants Disease Research Fields

Target:  

Cholinesterase (ChE) iGluR

(-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease .
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1
(±)-Huperzine A
(±)-Huperzine A
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1 Cited Publications
Cat. No.: HY-17388
CAS No.: 120786-18-7
Category:  

Huperziaceae Terpenoids Sesquiterpenes Huperzia serrata (Thunb. ex Murray) Trevis. Plants

Target:  

Drug Isomer Cholinesterase (ChE) iGluR

(±)-Huperzine A is the racemate of (-)-Huperzine A (HY-17387). (-)-Huperzine A is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease .
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Huperzine B
Huperzine B
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Cat. No.: HY-N2043
CAS No.: 103548-82-9
Category:  

Lycopodiaceae Alkaloids Piperidine Alkaloids Lycopodium serratum Thunb． Pyridine Alkaloids Plants

Target:  

Cholinesterase (ChE)

Huperzine B is a Lycopodium alkaloid isolated from Huperzia serrata and a highly selective acetylcholinesterase (AChE) inhibitor. Huperzine B can be uesd to can be used to improve Alzheimer's disease .
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Huperzine B (Standard)
Huperzine B (Standard)
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Cat. No.: HY-N2043R
CAS No.: 103548-82-9
Category:  

Lycopodiaceae Alkaloids Piperidine Alkaloids Lycopodium serratum Thunb． Pyridine Alkaloids Plants

Target:  

Reference Standards Cholinesterase (ChE)

Huperzine B (Standard) is the analytical standard of Huperzine B. This product is intended for research and analytical applications. Huperzine B is a Lycopodium alkaloid isolated from Huperzia serrata and a highly selective acetylcholinesterase (AChE) inhibitor. Huperzine B can be uesd to can be used to improve Alzheimer's disease .
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Huperzine C
Huperzine C
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Cat. No.: HY-122957
CAS No.: 163089-71-2
Category:  

Lycopodiaceae Alkaloids Lycopodium serratum Thunb． Plants

Target:  

Cholinesterase (ChE)

Huperzine C is an alkaloid isolated from Huperzia serrate. Huperzine C is an acetylcholinesterase (AChE) inhibotor, with an IC50 of 0.6 μM. Huperzine C can be used for the research of Alzheimer’s disease .
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(-)-Huperzine A-d4 hydrochloride
(-)-Huperzine A-d4 hydrochloride
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Cat. No.: HY-17387S1
Synonyms: Huperzine A-d4
(-)-Huperzine A-d4 hydrochloride is deuterated labeled (-)-Huperzine A (HY-17387). (-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease .
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Mimopezil
Mimopezil
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Cat. No.: HY-14795
CAS No.: 180694-97-7
Synonyms: ZT-1
Target:  

Cholinesterase (ChE)

Research Areas:  

Neurological Disease

Mimopezil (ZT-1) is an cholinesterase (ChE) inhibitor that rapidly degrades into the active metabolite Huperzine A (HY-17388) in water or aqueous organic solvents. After oral administration, Mimopezil is rapidly absorbed but has low bioavailability (0.37%) in rats. However, after metabolism, it is converted into Huperzine A, which accumulates in the blood and exhibits strong activity. Following intravenous administration, Mimopezil reaches higher blood concentrations and is also rapidly metabolized into Huperzine A .
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