25 Results for "

IFITM

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "IFITM" in MCE Product Catalog:

21
21 Publications Verification
Cat. No.: HY-U00434
CAS No.: 890405-51-3
Target:  

mTOR Autophagy Apoptosis

Research Areas:  

Infection Inflammation/Immunology

3BDO is a IFITM3 modulator and mTOR activator with antiviral and autophagy-inhibiting effects. 3BDO exhibits inhibitory activity against porcine coronaviruses. 3BDO increases the protein abundance of IFITM3, inhibits virus-cell membrane fusion, and blocks viral entry. 3BDO inhibits the entry of transmissible gastroenteritis virus, porcine epidemic diarrhea virus, and porcine respiratory coronavirus into host cells. 3BDO can be used for research on porcine coronavirus infection .
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3
3 Cited Publications
Cat. No.: HY-50856A
CAS No.: 941685-37-6
Synonyms: S-Ruxolitinib; S-INCB18424
Target:  

JAK

Research Areas:  

Cancer

Ruxolitinib (S enantiomer) (S-Ruxolitinib) is the S-enantiomer of Ruxolitinib (HY-50856). Ruxolitinib (S enantiomer) is an orally active, potent JAK inhibitor .
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1
1 Cited Publications
Cat. No.: HY-P86615
Synonyms: IFITM3; Interferon-induced transmembrane protein 3; Dispanin subfamily A member 2b; DSPA2b; Interferon-inducible protein 1-8U

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-N3540
CAS No.: 354553-35-8
Caraphenol A is a resveratrol trimer and is able to transiently reduce interferon-induced transmembrane (IFITM) protein expression. Caraphenol A safely enhances lentiviral vector gene delivery to hematopoietic stem and progenitor cells . Caraphenol A also inhibits human cystathionine β-synthase (hCBS) and human cystathionine γ- lyase (hCSE) with IC50s of 5.9 μM and 12.1 μM, respectively .
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Cat. No.: HY-155815
Purity:  97.60%
MS9715 is a selective NSD3 PROTAC degrader with a Kd value of 1.3 μM and a DC50 of 4.9 μM. MS9715 recruits the VHL E3 ligase to mediate the ubiquitination and degradation of NSD3. MS9715 downregulates oncogenes including CBLB, IFITM1 and MAP7. MS9715 induces Apoptosis. MS9715 is applicable to the research of hematological malignancies and lung cancer .
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Cat. No.: HY-RS06565
Research Areas:  

Others

IFITM1 Human Pre-designed siRNA Set A contains three designed siRNAs for IFITM1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS06566
Research Areas:  

Others

IFITM10 Human Pre-designed siRNA Set A contains three designed siRNAs for IFITM10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS06567
Research Areas:  

Others

IFITM2 Human Pre-designed siRNA Set A contains three designed siRNAs for IFITM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS06568
Research Areas:  

Others

IFITM3 Human Pre-designed siRNA Set A contains three designed siRNAs for IFITM3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS06569
Research Areas:  

Others

IFITM5 Human Pre-designed siRNA Set A contains three designed siRNAs for IFITM5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17924
Research Areas:  

Others

Ifitm3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ifitm3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS26669
Research Areas:  

Others

Ifitm1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ifitm1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS20165
Research Areas:  

Others

Ifitm1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ifitm1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS21869
Research Areas:  

Others

Ifitm2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ifitm2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24394
Research Areas:  

Others

Ifitm3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ifitm3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS28386
Research Areas:  

Others

Ifitm2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ifitm2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Cat. No.: HY-P992379
Synonyms: BAG3-H2L4

Target:  

Bcl-2 Family

Research Areas:  

Cancer

IB001 is a humanized anti-BAG3 antibody that inhibits BAG3, with a KD value of 14.4 nM for human BAG3. IB001 blocks BAG3-dependent monocyte/macrophage activation, interferes with the interaction between BAG3 and IFITM-2, and disrupts tumor microenvironment signaling pathways. IB001 inhibits tumor growth, reduces α-SMA-positive fibroblasts, and blocks BAG3-dependent IL-6 release. IB001 accumulates in a time-dependent manner in pancreatic ductal adenocarcinoma tumors. IB001 can be used for research related to pancreatic ductal adenocarcinoma .
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Cat. No.: HY-P89146
Synonyms: 1-8D; DSPA2c

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P89146A
Synonyms: 1-8D; DSPA2c

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P83321
Synonyms: 9-27; CD225; IFI17; LEU13; DSPA2a

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF, IP

Reactivity:  

Human

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