354553-35-8
Chemical Structure
Caraphenol A
- CAS No.: 354553-35-8
- Formula:C42H28O9
- Molecular Weight:676.67
InChIKey: ULEJGXIKBFHUOY-PIQPXYRBSA-N
SMILES: [H][C@]12[C@@H](OC3=C1C([C@@]4([C@H](OC5=C4C(C6=C(OC7=C6C2=CC(O)=C7)C8=CC=C(O)C=C8)=CC(O)=C5)C9=CC=C(O)C=C9)[H])=CC(O)=C3)C%10=CC=C(O)C=C%10
Biological Activity: Caraphenol A is a resveratrol trimer and is able to transiently reduce interferon-induced transmembrane (IFITM) protein expression. Caraphenol A safely enhances lentiviral vector gene delivery to hematopoietic stem and progenitor cells[1]. Caraphenol A also inhibits human cystathionine β-synthase (hCBS) and human cystathionine γ- lyase (hCSE) with IC50s of 5.9 μM and 12.1 μM, respectively[2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Caraphenol A | 99.71% | Caraphenol A is a resveratrol trimer and is able to transiently reduce interferon-induced transmembrane (IFITM) protein expression. Caraphenol A safely enhances lentiviral vector gene delivery to hematopoietic stem and progenitor cells. Caraphenol A also inhibits human cystathionine β-synthase (hCBS) and human cystathionine γ- lyase (hCSE) with IC50s of 5.9 μM and 12.1 μM, respectively. | ||||||||||||||||||||
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References
- [1]. Ozog S, et al. Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes. Blood. 2019 Oct 17;134(16):1298-1311. [Content Brief]
- [2]. Niu W, et al. Discovery of selective cystathionine β-synthase inhibitors by high-throughput screening with a fluorescent thiol probe. Medchemcomm. 2016 Nov 15;8(1):198-201. [Content Brief]
