26 Results for "

IL-5 Antibody

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "IL-5 Antibody" in MCE Product Catalog:

Cat. No.: HY-P810893
Synonyms: Interleukin-5, IL-5, B-cell differentiation factor I, EosinophIL differentiation factor, T-cell replacing factor, TRF, IL5

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat

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1 Cited Publications
Cat. No.: HY-P9923A
CAS No.: 1044511-01-4
Synonyms: MEDI-563 (anti-IL5RA); BIW-8405 (anti-IL5RA); KHK4563 (anti-IL5RA)
Benralizumab (anti-IL5RA) (MEDI-563 (anti-IL5RA); BIW-8405 (anti-IL5RA)) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma study .
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1 Cited Publications
Cat. No.: HY-P9923
CAS No.: 1044511-01-4
Synonyms: MEDI-563; BIW-8405; KHK4563
Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma .
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Cat. No.: HY-P9945
CAS No.: 196078-29-2
Synonyms: SB 240563
Mepolizumab (SB 240563) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma .
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Cat. No.: HY-P990774
CAS No.: 2768386-15-6
Synonyms: ASP-7266; TRAB-1; UPB-101

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
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Cat. No.: HY-P9945A
CAS No.: 196078-29-2

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Mepolizumab (anti-IL5) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma .
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Cat. No.: HY-P990213

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-Mouse/Human IL-5 Antibody (TRFK5) is a rat-derived anti-mouse IL-5 IgG1 κ type antibody inhibitor. Anti-Mouse/Human IL-5 Antibody (TRFK5) can significantly decrease eosinophils. Anti-Mouse/Human IL-5 Antibody (TRFK5) shows potent anti- inflammation effect on pulmonary inflammation and asthma .
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Cat. No.: HY-P99371
CAS No.: 2283348-97-8
Synonyms: AK002; Antolimab

Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology

Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis .
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Cat. No.: HY-P9949
CAS No.: 241473-69-8
Synonyms: Sch 55700; CDP-835; JES1-39D10

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Reslizumab (Sch 55700) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab is effective in neutralizing the function of IL-5. Reslizumab has high binding affinity for human IL-5, with KD values of 109 pM and 4.3 pM in the the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively .
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Cat. No.: HY-P991266

Research Areas:  

Inflammation/Immunology

SM-17 is a human monoclonal antibody targeting IL-17RB. SM-17 binds to human IL-17RB, inhibits the dimerization of IL-17RA/IL-17RB, blocks IL-25-induced phosphorylation of ERK1/2 and STAT5, and suppresses Th2-mediated inflammatory responses. SM-17 inhibits the secretion of IL-5, IL-9, IL-13 and IL-4, impairs the proliferation/expansion of ILC2 and Th2 cells, and restores filaggrin expression. SM-17 reduces immune cell infiltration, epidermal hyperplasia, goblet cell hyperplasia, collagen deposition, ear swelling and scratching behavior in animal models. SM-17 can be used in research related to atopic dermatitis and allergic asthma .
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Cat. No.: HY-P99850
CAS No.: 2243274-14-6
Synonyms: GSK-3511294

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Depemokimab (GSK-3511294) is a long-acting anti-IL-5 monoclonal antibody. Depemokimab can be used for research of asthma .
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Cat. No.: HY-P991712
CAS No.: 3031358-43-4

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Revbekitug is a humanized IgG1κ antibody targeting IL-5. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P991633

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

TQC2938 is a humanized IgG2 monoclonal antibody inhibitor targeting Stimulation-2 (ST2). TQC2938 inhibits the ST2/IL-33 signaling pathway, reduces the level of downstream Th2 cytokines (such as IL-4, IL-5, and IL-13) and eosinophils as well as other inflammatory cells. TQC2938 can be used for inflammatory diseases like asthma research .
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Cat. No.: HY-P990452

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-IL-5 Antibody is a CHO-expressed humanized antibody that targets IL-5. The Anti-IL-5 Antibody is composed of huIgG4 heavy chains and huκ light chains, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-IL-5 Antibody can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-P991144
CAS No.: 3021525-26-5

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Lasrekibart is a humanized monoclonal antibody targeting human interleukin 5 (IL-5). Lasrekibart specifically binds to IL-5, blocking the interaction between IL-5 and its receptor, thus exerting immunosuppressive and anti-inflammatory activities. Lasrekibart is promising for research of allergic and inflammatory diseases, such as asthma .
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Cat. No.: HY-P990058
CAS No.: 2643349-04-4

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Varokibart (TEV-53275) is a human IgG4λ antibody targeting IL5 .
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Cat. No.: HY-P991599

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

SHR-1703 is a long-acting humanized anti-IL-5 IgG1 monoclonal antibody. SHR-1703 can selectively recognize and bind to IL-5, blocking the binding of IL-5 to the α chain of the receptor on the surface of eosinophils, thereby inhibiting the proliferation, activation, and migration of eosinophils, and ultimately reducing eosinophil-mediated inflammation and damage. SHR-1703 can be used in the research of eosinophil-related diseases, such as eosinophilic asthma. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P85018
Synonyms: IL5; Interleukin-5; IL-5; B-cell differentiation factor I; EosinophIL differentiation factor; T-cell replacing factor; TRF; IL-5 nanobody;

Host:  

Mouse

Application:  

ELISA

Reactivity:  

Human

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Cat. No.: HY-P81483
Synonyms: IL-5 Receptor alpha; interleukin 5 receptor; alpha; IL5R; CD125; CDw125; HSIL5R3

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P81483A
Synonyms: IL-5 Receptor alpha; interleukin 5 receptor; alpha; IL5R; CD125; CDw125; HSIL5R3

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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