12 Results for "

K1 peptide

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "K1 peptide" in MCE Product Catalog:

Cat. No.: HY-P5964
CAS No.: 2973365-72-7
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

K1 peptide is a high-affinity peptide ligand for GABAA receptor-associated protein (GABARAP) .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P1925A
CAS No.: 1222186-26-6
Research Areas:  

Cancer

GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice .
loading...
    loading...
Cat. No.: HY-P4146
CAS No.: 2805997-46-8
Synonyms: BI 456906
Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
loading...
    loading...
Cat. No.: HY-P5964A
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

K1 peptide TFA is a high-affinity peptide ligand for GABAA receptor-associated protein (GABARAP) .
loading...
    loading...
Cat. No.: HY-P5203
CAS No.: 2764845-22-7
Synonyms: EntK1
Target:  

Bacterial

Research Areas:  

Infection

Enterocin K1 (EntK1) is a bacteriocin. Enterocin K1 is a ribosomal synthetic peptide. Enterocin K1 specifically targets Enterococcus faecalis via the Eep protein on the bacterial membrane. Enterocin K1 displays a potent antibacterial activity against VRE. Enterocin K1 can be used for related studies of VRE infections .
loading...
    loading...
Cat. No.: HY-114645
CAS No.: 1643958-89-7
Purity:  98.49%
Target:  

PDK-1

Research Areas:  

Cancer

PDK1-IN-RS2 is a mimic of peptide docking motif (PIFtide) and is a substrate-selective PDK1 inhibitor with a Kd of 9 μM. PDK1-IN-RS2 suppresses the activation of the downstream kinases S6K1 by PDK1 .
loading...
    loading...
Cat. No.: HY-P4146A
Synonyms: BI 456906 TFA
Target:  

GLP Receptor GCGR

Research Areas:  

Metabolic Disease

Survodutide (BI 456906) TFA is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide TFA, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide TFA has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
loading...
    loading...
Cat. No.: HY-P4146B
Synonyms: BI 456906 sodium
Target:  

GLP Receptor GCGR

Research Areas:  

Metabolic Disease

Survodutide (BI 456906) sodium is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide sodium, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide sodium has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake .
loading...
    loading...
Cat. No.: HY-P0165B
CAS No.: 1022150-16-8
Synonyms: ITM077 acetate; R1583 acetate; BIM51077 acetate
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Taspoglutide (R1583) acetate is an agonist of the glucagon-like peptide 1 receptor (GLP-1R) with an Ki value of 1.1 nM. Taspoglutide acetate induces cAMP accumulation in CHO-K1 cells expressing human GLP-1R (EC50 = 0.06 nM). Taspoglutide acetate decreases blood levels of glucose and increases blood levels of insulin in a glucose tolerance test in Zucker diabetic obese rats. Taspoglutide acetate reduces blood levels of gastric inhibitory polypeptide (GIP), plasma levels of triglycerides, and body weight in the same model .
loading...
    loading...
Cat. No.: HY-113513
CAS No.: 92008-51-0
Category:  

Animals Lipids

Target:  

Others

5-HEPE is an active metabolite of eicosapentaenoic acid. It is formed from EPA by 5-lipoxygenase (5-LO). 5(S)-HEPE is an agonist of G protein-coupled receptor 119 (GPR119). 5(S)-HEPE increases cAMP accumulation in CHO-K1 cells expressing human GPR119 when used at a concentration of 10 μM. 5(S)-HEPE increases glucose-induced insulin secretion from MING6 insulinoma pancreatic islets and glucagon-like peptide 1 (GLP-1) secretion from HuTu 80 adenocarcinoma cells when used at a concentration of 10 μM. Serum levels of 5(S)-HEPE are elevated in patients with hyperlipidemia.
loading...
    loading...
Cat. No.: HY-P10843
Target:  

Estrogen Receptor/ERR

Research Areas:  

Cancer

R4K1 is a cell-permeable stapled peptide. R4K1 binds to the estrogen receptor (ER) α with high affinity and inhibits its interaction with coactivators. R4K1 can enter breast cancer cells to regulate gene transcription and inhibit cell proliferation. R4K1 can be used in the study of cancer .
loading...
    loading...
Cat. No.: HY-P1602
CAS No.: 123276-94-8
Target:  

Bacterial

Research Areas:  

Infection

Apidaecin IB is a insect antimicrobial peptide, with minimum inhibitory concentration (MIC) values of 8 μM for E. coli (ML35, O18K1H7 and ATCC 25922).
loading...
    loading...
  • 1