2 Results for "

KRAS G12C Peptide TFA

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "KRAS G12C Peptide TFA" in MCE Product Catalog:

Cat. No.: HY-P11357A
Target:  

IFNAR

Research Areas:  

Cancer

KRAS G12C Peptide TFA is the trifluoroacetate salt of KRAS G12C Peptide (HY-P11357). KRAS G12C Peptide is a specific peptide derived from the Kirsten rat sarcoma virus (KRAS) gene carrying the G12C oncogenic mutation. KRAS G12C Peptide induces responses like IFN-γ secretion and cytotoxicity. KRAS G12C Peptide can be used for the study of immune responses against KRAS G12C-mutant tumors .
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Cat. No.: HY-P2265A
CAS No.: 2896737-31-6
Target:  

SOS1 Ras

Research Areas:  

Cancer

SAH-SOS1A TFA is a peptide-based SOS1/KRAS protein interaction inhibitor. SAH-SOS1A TFA binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity (EC50=106-175 nM). SAH-SOS1A TFA directly and independently blocks nucleotide association. SAH-SOS1A TFA impairs KRAS-driven cancer cell viability and exerts its effects by on-mechanism blockade of the ERK-MAPK phosphosignaling cascade downstream of KRAS .
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