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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
M39-20 cells
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "M39-20 cells" in MCE Product Catalog:
Cat. No.: HY-137255
CAS No.: 64936-83-0
Synonyms: 3-Sulfotaurolithocholic acid disodium
Synonyms: Sulfolithocholic acid disodium; LCAS disodium
Cat. No.: HY-W587430
CAS No.: 64936-82-9
Synonyms: Glycolithocholate sulfate disodium; Sulfolithocholylglycine disodium; SLCG disodium
Research Areas:
Glycolithocholic acid 3-sulfate disodium is a GPR39 agonist with EC50s of 47.9 and 66.8 μM (absence of Zn 2+) and 8 and 8.7 μM (presence of Zn 2+) in M39-20 and hGPR39-2 cells, respectively. Glycolithocholic acid 3-sulfate disodium stimulates GPR39 receptors to initiate intracellular calcium signaling, independent of Zn 2+ binding sites H17 and H19. Glycolithocholic acid 3-sulfate disodium also inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate disodium can be used for the research of HIV infection and gallbladder disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
