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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
MRPS2
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "MRPS2" in MCE Product Catalog:
9
9 Publications Verification
Target:
Forschungsgebiete:
CP-100356 hydrochloride is an orally active dual MDR1 (P-gp)/BCRP inhibitor, with an IC50s of 0.5 and 1.5 µM for inhibiting MDR1-mediated Calcein-AM transport and BCRP-mediated Prazosin transport, respectively. CP-100356 hydrochloride is also a weak inhibitor of OATP1B1 (IC50=∼66 µM). CP-100356 hydrochloride is devoid of inhibition against MRP2 and major human P450 enzymes (IC50>15 µM) .
4
4
Category:
4
4 Cited Publications
Art. -Nr.: HY-N1423B
CAS. Nr.: 1192657-83-2
2
2 Cited Publications
Art. -Nr.: HY-N0248
CAS. Nr.: 58316-41-9
Category:
Infection Triterpenes Terpenoids Plants Umbelliferae Disease Research Fields Carphephorus corymbosus (Nutt.) Torr. & A.Gray
Target:
2
Target:
Forschungsgebiete:
Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG) [2].
1
1 Cited Publications
Synonyms: Benzoylaconitine; Isaconitine; Pikraconitin
1
1 Cited Publications
Art. -Nr.: HY-D0194
CAS. Nr.: 111843-78-8
Target:
Forschungsgebiete:
5(6)-Carboxy-2',7'-dichlorofluorescein is an ideal substrate for MRP2 vesicular transport assay, with excellent detection and transport properties .
1
1 Cited Publications
Art. -Nr.: HY-N7755
CAS. Nr.: 14982-12-8
Forschungsgebiete:
Estradiol 3-glucuronide sodium is an estrogen metabolite, which is a glucuronide conjugate formed by the catalysis of uridine diphosphate glucuronosyltransferase in tissues such as the liver from Estradiol (HY-B0141). Estradiol 3-glucuronide sodium is a potent substrate of Mrp2, with an S50 of 55.7 μM. Estradiol 3-glucuronide sodium achieves hepatobiliary transport in hepatocytes through basolateral uptake via OATP1B1, OATP1B3 and OATP2B1, as well as apical efflux via MRP2 and BCRP [2] .
1
1 Cited Publications
Art. -Nr.: HY-W585842
CAS. Nr.: 15270-30-1
Forschungsgebiete:
Estradiol 3-glucuronide is an estrogen metabolite, which is a glucuronide conjugate formed from Estradiol (HY-B0141) via catalysis by uridine diphosphate glucuronosyltransferases in tissues such as the liver. Estradiol 3-glucuronide is a potent substrate of Mrp2, with an S50 value of 55.7 μM. Estradiol 3-glucuronide achieves hepatobiliary transport in hepatocytes through basolateral uptake via OATP1B1, OATP1B3 and OATP2B1, as well as apical efflux via MRP2 and BCRP [2] .
Art. -Nr.: HY-W008226
CAS. Nr.: 480-66-0
Synonyms: 2,4,6-trihydroxyacetophenone; 1-(2,4,6-Trihydroxyphenyl)ethanone
Category:
Metabolic Disease Plants Curcuma comosa Roxb. Infection other families Ketones, Aldehydes, Acids Phenols Polyphenols Disease Research Fields Zingiberaceae
Target:
Art. -Nr.: HY-N1423S
CAS. Nr.: 1201918-15-1
Art. -Nr.: HY-D1078
CAS. Nr.: 127770-45-0
Art. -Nr.: HY-B0501
CAS. Nr.: 119478-55-6
Synonyms: CP 76136-27
Target:
Forschungsgebiete:
Danofloxacin mesylate (CP 76136-27) is a fluoroquinolone used as a veterinary drug. Danofloxacin mesylate has a broad spectrum of bactericidal activity, mainly inhibiting the DNA cycloenzyme of the bacteria. In addition, Danofloxacin mesylate is a substrate for ATP-dependent efflux transporters (P-gp and MRP2) [2] .
Target:
Art. -Nr.: HY-W353102
CAS. Nr.: 1806-98-0
Category:
Monophenols Metabolic Disease Phenols Endogenous metabolite Disease Research Fields Endocrinology Steroids
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Art. -Nr.: HY-W013105
CAS. Nr.: 338950-81-5
Synonyms: N-Cholylglycine sodium salt, 98%
Art. -Nr.: HY-RS08678
Target:
Forschungsgebiete:
MRPS2 Human Pre-designed siRNA Set A contains three designed siRNAs for MRPS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-N0406
CAS. Nr.: 861691-37-4
Category:
other families Flavonoids Plants Disease Research Fields Inflammation/Immunology Isoflavones
Target:
Art. -Nr.: HY-N4108
CAS. Nr.: 33676-00-5
Category:
Phyllanthus urinaria Linn. Lignans Euphorbiaceae Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
