Estradiol 17-(β-D-Glucuronide) (sodium)

Cat. No.: HY-129987 Purity: 99.46%: FAQs
Data Sheet SDS COA Handling Instructions

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Estradiol 17-(β-D-Glucuronide) sodium, a metabolite of estrogen, is well known to cause intrahepatic cholestasis in humans.

For research use only. We do not sell to patients.

Estradiol 17-(β-D-Glucuronide) (sodium) Chemical Structure

CAS No. : 15087-02-2

Size	Price	Stock	Quantity
5 mg	USD 390	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 624	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Estradiol 17-(β-D-Glucuronide) (sodium):

Estradiol 17-(β-D-Glucuronide) Get quote

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Purity & Documentation
References
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Description

Estradiol 17-(β-D-Glucuronide) sodium, a metabolite of estrogen, is well known to cause intrahepatic cholestasis in humans^[1].

Molecular Weight

470.49

Formula

C₂₄H₃₁NaO₈

CAS No.

15087-02-2

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC[C@@H]2O[C@]3([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O[Na])=O)([H])[C@@]4([H])[C@](C5=C(C=C(O)C=C5)CC4)([H])CC1

Structure Classification

Steroids

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 66.67 mg/mL (141.70 mM; ultrasonic and adjust pH to 3 with 1M HCl; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1254 mL	10.6272 mL	21.2544 mL
5 mM	0.4251 mL	2.1254 mL	4.2509 mL
10 mM	0.2125 mL	1.0627 mL	2.1254 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.46%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (255 KB) HNMR (297 KB) LCMS (87 KB)

Handling Instructions (2659 KB)

References

[1]. Kinbara S, et al. Improvement of estradiol-17 beta-D-glucuronide-induced cholestasis by sodium tauroursodeoxycholate therapy in rats. Scand J Gastroenterol. 1997;32(9):947-952. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1254 mL	10.6272 mL	21.2544 mL	53.1361 mL
	5 mM	0.4251 mL	2.1254 mL	4.2509 mL	10.6272 mL
	10 mM	0.2125 mL	1.0627 mL	2.1254 mL	5.3136 mL
	15 mM	0.1417 mL	0.7085 mL	1.4170 mL	3.5424 mL
	20 mM	0.1063 mL	0.5314 mL	1.0627 mL	2.6568 mL
	25 mM	0.0850 mL	0.4251 mL	0.8502 mL	2.1254 mL
	30 mM	0.0708 mL	0.3542 mL	0.7085 mL	1.7712 mL
	40 mM	0.0531 mL	0.2657 mL	0.5314 mL	1.3284 mL
	50 mM	0.0425 mL	0.2125 mL	0.4251 mL	1.0627 mL
	60 mM	0.0354 mL	0.1771 mL	0.3542 mL	0.8856 mL
	80 mM	0.0266 mL	0.1328 mL	0.2657 mL	0.6642 mL
	100 mM	0.0213 mL	0.1063 mL	0.2125 mL	0.5314 mL