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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
133 Results for "
Mammals
" in MedChemExpress (MCE) Product Catalog:
Products (133)
133 Results for "Mammals" in MCE Product Catalog:
92
92
92 Publications Verification
Cat. No.: HY-N0322A
Target:
(Note: This product is a mixture of Cholesterol and Methyl-β-cyclodextrin. The product specifications below only indicate the effective content of Cholesterol.)
43
43 Cited Publications
Synonyms: (-)-Bicuculline methochloride
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Research Areas:
Bicuculline ((+)-Bicuculline; d-Bicuculline) methochloride is a selective GABAA receptor antagonist with an IC50 value of 3 μM. Bicuculline methochloride induces clonic tonic convulsions in mammals and can also be used to block Ca 2+ activated potassium channels. Bicuculline methochloride can be used in studies of epilepsy and other related psychiatric disorders .
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41 Cited Publications
Cat. No.: HY-108882C
CAS No.: 9003-98-9
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Research Areas:
DNase I is an enzyme that degrades DNA. DNase I is mainly produced by digestive system organs, such as the pancreas and parotid gland. Three types of DNase I are known in mammals: pancreatic type, parotid type, and pancreatico-parotid type. DNase I plays a key role in the cleavage of extracellular DNA, and is critical for limiting inflammatory responses and maintaining homeostasis. DNase I is responsible for digesting extracellular nucleoproteins, which may be essential for preventing autoimmune reactions. Decreased DNase I activity may be associated with the occurrence and development of systemic lupus erythematosus (SLE). DNase I (filtered) is filtered through a 0.22 μM membrane and is not tested for pyrogenicity .
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41 Cited Publications
Cat. No.: HY-108882B
CAS No.: 9003-98-9
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Research Areas:
DNase I is an enzyme that degrades DNA. DNase I is mainly produced by digestive system organs, such as the pancreas and parotid gland. Three types of DNase I are known in mammals: pancreatic type, parotid type, and pancreatico-parotid type. DNase I plays a key role in the cleavage of extracellular DNA, and is critical for limiting inflammatory responses and maintaining homeostasis. DNase I is responsible for digesting extracellular nucleoproteins, which may be essential for preventing autoimmune responses. Decreased DNase I activity may be associated with the onset and progression of systemic lupus erythematosus (SLE). DNase I (RNase & Protease free) is a molecular biology-grade DNase I purified by chromatography to remove RNase and protease .
13
Cholesterol (synthetic) is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol (synthetic) plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins . Cholesterol (synthetic) is also an endogenous estrogen-related receptor α (ERRα) agonist .
10
Category:
Cardiovascular Disease Anti-aging Pyridine Alkaloids Solanum lycopersicum L. Plants Alkaloids Solanaceae Disease Research Fields Inflammation/Immunology Steroids
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10
Category:
Cardiovascular Disease Solanum lycopersicum L. Plants Solanaceae Disease Research Fields Steroids
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9
9 Cited Publications
Synonyms: PQQ; Methoxatin
Category:
Quinones Microorganisms Animals Benzene Quinones Endogenous metabolite Disease Research Fields Inflammation/Immunology
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9
9 Cited Publications
Synonyms: PQQ disodium salt; Methoxatin disodium salt
Category:
Quinones Microorganisms Benzene Quinones Endogenous metabolite Disease Research Fields Inflammation/Immunology
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2
2 Cited Publications
Synonyms: Chromium acetate; Chromic acetate; Chromium triacetate
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Chromium(III) acetate (Chromic acetate) is an AMPK inhibitor that promotes lipogenesis by inhibiting AMPK phosphorylation. Chromium(III) acetate has low toxicity in mammals, with an LD50 of 2365 mg/kg in rats .
2
2 Cited Publications
Cat. No.: HY-W014971
CAS No.: 343-94-2
2
Research Areas:
Temephos (Temefos) is an orally active, blood-brain barrier-permeable organophosphate insecticide and AChE inhibitor. By irreversibly inhibiting AChE to induce cholinergic overactivation, Temephos effectively blocks larval development of Aedes aegypti (yellow fever mosquito) and Aedes albopictus (Asian tiger mosquito), and is commonly used in studies related to Dengue Virus, Zika Virus and other relevant pathogens. Temephos exhibits genotoxicity and neurodevelopmental toxicity, and may also cause liver injury, reproductive system abnormalities and cholinergic poisoning symptoms in mammals. Temephos tends to accumulate in adipose tissues and aquatic organisms, and is excreted via feces after metabolism through oxidation and hydrolysis. Note that CYP-mediated metabolic detoxification may reduce the actual larvicidal efficacy of Temephos against some mosquito species. Temephos can be used in research related to dengue fever, Zika virus disease, chikungunya and dracunculiasis .
1
1 Cited Publications
Cat. No.: HY-W018035
CAS No.: 473-81-4
Synonyms: Glyceric Acid (20% in Water,ca.2 mol/L)
Category:
Microorganisms Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
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1
Target:
1
1 Cited Publications
Cat. No.: HY-P0241
CAS No.: 87096-84-2
Category:
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1
1 Cited Publications
Cat. No.: HY-148163
CAS No.: 28210-41-5
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Research Areas:
Polystyrene sulfonic acid (30% in water) is a potentially toxic hazardous substance. Polystyrene-derived microplastics (PS-MPs) are harmful to zebrafish hearts and induce male reproductive toxicity in mice. MCE offers Polystyrene products in solution packaging .
1
1 Cited Publications
Cat. No.: HY-110406
CAS No.: 33964-75-9
Category:
Human Gut Microbiota Metabolites Metabolic Disease Endogenous metabolite Disease Research Fields
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
