1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Pyrroloquinoline quinone

Pyrroloquinoline quinone  (Synonyms: PQQ; Methoxatin)

Cat. No.: HY-100196 Purity: 99.65%
COA Handling Instructions

Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function.

For research use only. We do not sell to patients.

Pyrroloquinoline quinone Chemical Structure

Pyrroloquinoline quinone Chemical Structure

CAS No. : 72909-34-3

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Based on 1 publication(s) in Google Scholar

Other Forms of Pyrroloquinoline quinone:

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Description

Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function[1][2].

IC50 & Target[1]

Microbial Metabolite

 

Human Endogenous Metabolite

 

In Vitro

Mouse pups born to and nursing from Pyrroloquinoline quinone (PQQ)-deprived dams have a compromised immune response as well as alopecia, a hunched posture, and a susceptibility to aortic aneurysms[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

330.21

Formula

C14H6N2O8

CAS No.
SMILES

O=C(C(N1)=CC(C2=O)=C1C3=C(N=C(C(O)=O)C=C3C(O)=O)C2=O)O

Structure Classification
Source

cultures of methylotropic bacteria and tissues of mammals

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 1 mg/mL (3.03 mM; ultrasonic and warming and heat to 60°C)

DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0284 mL 15.1419 mL 30.2838 mL
5 mM --- --- ---
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 1 mg/mL (3.03 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 99.65%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Pyrroloquinoline quinone
Cat. No.:
HY-100196
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