33964-75-9
33964-75-9
Chemical Structure
13(S)-HPODE
- CAS 番号: 33964-75-9
- Formula:C18H32O4
- Molecular Weight:312.44
IUPAC Name: (S,9Z,11E)-13-hydroperoxyoctadeca-9,11-dienoic acid
InChIKey: JDSRHVWSAMTSSN-IRQZEAMPSA-N
SMILES: CCCCC[C@H](OO)/C=C/C=C\CCCCCCCC(O)=O
Biological Activity: 13(S)-HPODE is a linoleic acid metabolite found in several plants and mammals.
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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13(S)-HPODE | 95.05% | 13(S)-HPODE is a linoleic acid metabolite found in several plants and mammals. | ||||||||||||||||||||
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(±)13-HpODE | 99.9% | (±)13-HpODE (13-hydroperoxylinoleic acid) is a racemic mixture of hydroperoxides, which is produced by the oxidation of linoleic acid by lipoxygenase. | ||||||||||||||||||||
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(R)-Coriolic acid | 13(R)-HODE is the opposite enantiomer of the 13(S)-HODE produced when linoleic acid is incubated with soybean lipoxygenase. The presence of 13(R)-HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism.1 13(R)-HODE is a weak (IC50=2.7 μM) inhibitor of U-46619-induced platelet aggregation. | |||||||||||||||||||||
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(±)-Coriolic acid | 98.70% | (±)-Coriolic acid ((±)-13-HODE) is one of the two racemic monohydroxy fatty acids produced by non-enzymatic oxidation of linoleic acid. (±)-Coriolic acid induces TNF production in macrophages and upregulates Scavenger Receptor, thereby promoting the uptake of oxidized low-density lipoprotein. (±)-Coriolic acid induces the expression of cell adhesion molecules in endothelial cells. (±)-Coriolic acid can be used in research on psoriasis, atherosclerosis, and triple-negative breast cancer. | ||||||||||||||||||||
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(S)-Coriolic acid | 99.0% | (S)-Coriolic acid (13(S)-HODE), the product of 15-lipoxygenase (15-LOX) metabolism of linoleic acid, functions as the endogenous ligand to activate PPARγ. (S)-Coriolic acid is an important intracellular signal agent and is involved in cell proliferation and differentiation in various biological systems. (S)-Coriolic acid induces mitochondrial dysfunction and airway epithelial injury. | ||||||||||||||||||||
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9(S)-HpODE | 98.0% | 9(S)-HpODE is produced by the action of arachidonate 5-LO on linoleic acid. It can be further metabolized by potato hydroperoxide dehydratase to colneleic acid. | ||||||||||||||||||||
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(±)9-HpODE | 98.9% | (±)9-HpODE is a long chain lipid hydroperoxide, is a product of linoleic acid peroxidation. (±)9-HpODE can induce oxidation of intracellular glutathione (GSH). (±)9-HpODE also exhibits antimicrobial activity against various fungal and bacterial pathogens. | ||||||||||||||||||||
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13-Hydroperoxy-9(E),11(E)-octadecadienoic acid | 13-Hydroperoxy-9(E),11(E)-octadecadienoic acid is an ester product. | |||||||||||||||||||||
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9-Hydroperoxy-10(E),12(E)-octadecadienoic acid | 9-Hydroperoxy-10(E),12(E)-octadecadienoic acid ((10E,12E)-9-Hydroperoxyoctadeca-10,12-dienoic acid) is an ester product. | |||||||||||||||||||||
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15(S)-Hydroperoxy-11(Z),13(E)-eicosadienoic acid | 98.8% | 15(S)-Hydroperoxy-11(Z),13(E)-eicosadienoic acid is an ester product. | ||||||||||||||||||||
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β-Dimorphecolic acid | β-Dimorphecolic acid is an ester product. | |||||||||||||||||||||
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