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Pathways Recommended:	Metabolic Enzyme/Protease

Results for "

Mitochondrial Cytochrome P450 Enzyme

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Cytochrome P450 (3) Mitochondrial Metabolism (1) Antibiotic (3) Apoptosis (3) Bacterial (3) Isotope-Labeled Compounds (1) Necroptosis (3) Reference Standards (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (2) Infection (3)

Inhibitors & Agonists

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: Cytochrome P450 Mitochondrial Metabolism Mitophagy Peroxidase Enzyme E1/E2/E3 Enzyme Carnosine-cleaving Enzyme Proteolytic Enzyme Endothelin-Converting Enzyme (ECE) Angiotensin-converting Enzyme (ACE) IRE1 NEDD8-activating Enzyme IDE TET Protein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1218

Sulfaphenazole 10+ Cited Publications	Cytochrome P450 Antibiotic Bacterial Necroptosis Apoptosis	Infection Cardiovascular Disease
Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion .

HY-B1218R

Sulfaphenazole (Standard)	Reference Standards Cytochrome P450 Antibiotic Bacterial Necroptosis Apoptosis	Infection Cardiovascular Disease
Sulfaphenazole (Standard) is the analytical standard of Sulfaphenazole. This product is intended for research and analytical applications. Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion .

HY-B1218S

Sulfaphenazole-d4	Isotope-Labeled Compounds Cytochrome P450 Antibiotic Bacterial Necroptosis Apoptosis	Infection
Sulfaphenazole-d₄ is the deuterium labeled Sulfaphenazole (HY-B1218). Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion .

HY-106396

Ro 23-7553	Mitochondrial Metabolism	Cancer
Ro 23-7553 is a mitochondrial inhibitor. Ro 23-7553 promotes chondrocyte differentiation at physiological concentrations, while supraphysiological concentrations inhibit both proliferation and differentiation. Ro 23-7553 can be used for the study of cancer .

Species:	Human (2)
Tag:	SUMO (2) His (2)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P72163

	CYP11B2 Protein, Human (His-SUMO) ALDOS; Aldosterone synthase; Aldosterone-synthesizing Enzyme; C11B2_HUMAN; CYP11B2; CYPXIB2; Cytochrome P-450Aldo; Cytochrome P-450C18; Cytochrome P450 11B2; Cytochrome P450 11B2; Mitochondrial; Mitochondrial; P-450Aldo; P-450C18; Steroid 18-hydroxylase	Human	E. coli
	CYP11B2 Protein, a cytochrome P450 monooxygenase, synthesizes aldosterone, pivotal for salt and water balance, impacting blood pressure and cardiovascular health. Mechanistically, it orchestrates three oxidative reactions, forming aldosterone, utilizing molecular oxygen and a mitochondrial transfer system. Additionally, CYP11B2 may be involved in the androgen metabolic pathway, expanding its physiological roles. CYP11B2 Protein, Human (His-SUMO) is the recombinant human-derived CYP11B2 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P705925

	CYP11A1 Protein, Human (His, SUMO) Cholesterol 20 22 desmolase; Cholesterol desmolase; Cholesterol monooxygenase (side chain cleaving); Cholesterol side chain cleavage Enzyme; Cholesterol side chain cleavage Enzyme Mitochondrial; Cholesterol side-chain cleavage Enzyme; CP11A_HUMAN; CYP11A; CYP11A1; CYPXIA1; Cytochrome P450 11A1; Cytochrome P450 11A1 Mitochondrial; Cytochrome P450 family 11 subfamily A polypeptide 1; Cytochrome P450 subfamily XIA; Cytochrome P450(scc); Cytochrome P450C11A1; Mitochondrial; P450SCC; Steroid 20 22 lyase	Human	E. coli

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Cat. No.	Product Name	Chemical Structure

HY-B1218S

Sulfaphenazole-d4
Sulfaphenazole-d₄ is the deuterium labeled Sulfaphenazole (HY-B1218). Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion .

Sulfaphenazole-d4

Sulfaphenazole-d₄ is the deuterium labeled Sulfaphenazole (HY-B1218). Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion .

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81223

	CYP11A1 Antibody 2 Publications Verification Cholesterol 20 22 desmolase antibody Cholesterol desmolase antibody; Cholesterol monooxygenase (side chain cleaving) antibody; Cholesterol side chain cleavage Enzyme antibody; Cholesterol side chain cleavage Enzyme Mitochondrial antibody; Cholesterol side-chain cleavage Enzyme antibody; CP11A_HUMAN antibody; CYP11A antibody; CYP11A1 antibody; CYPXIA1 antibody; Cytochrome P450 11A1 antibody; Cytochrome P450 11A1 Mitochondrial antibody; Cytochrome P450 family 11 subfamily A polypeptide 1 antibody; Cytochrome P450 subfamily XIA antibody; Cytochrome P450(scc) antibody; Cytochrome P450C11A1 antibody; Mitochondrial antibody; P450SCC antibody; Steroid 20 22 lyase antibody;	WB, IHC-P, IHC-F, ICC/IF	Human, Mouse, Rat
	CYP11A1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to CYP11A1.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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