1. Search Result
Search Result
Results for "

NO-red

" in MedChemExpress (MCE) Product Catalog:

132

Inhibitors & Agonists

3

Fluorescent Dye

2

Biochemical Assay Reagents

2

Peptides

26

Natural
Products

11

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108357
    6-Diazo-5-oxo-L-nor-Leucine
    10+ Cited Publications

    L-6-Diazo-5-oxoNOrleucine; DON

    Glutaminase Bacterial Influenza Virus Antibiotic Infection Cancer
    6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .
    6-Diazo-5-oxo-L-nor-Leucine
  • HY-112885B
    nor-NOHA monoacetate
    5 Publications Verification

    Nω-Hydroxy-NOr-L-arginine moNOacetate

    Arginase Apoptosis Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
    nor-NOHA monoacetate is a selective and reversible arginase inhibitor. nor-NOHA monoacetate induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA monoacetate has anti-leukemic activity. nor-NOHA monoacetate can used in study of endothelial dysfunction, immunosuppression and metabolism .
    nor-NOHA monoacetate
  • HY-12646
    Rhosin hydrochloride
    Maximum Cited Publications
    40 Publications Verification

    Ras Apoptosis Cancer
    Rhosin hydrochloride is a potent, specific RhoA subfamily Rho GTPases inhibitor. Rhosin hydrochloride specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin hydrochloride induces cell apoptosis . Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability .
    Rhosin hydrochloride
  • HY-112885A
    nor-NOHA acetate
    5 Publications Verification

    Nω-Hydroxy-NOr-L-arginine acetate

    Arginase Apoptosis Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
    nor-NOHA acetate is a selective and reversible Arginase inhibitor. nor-NOHA acetate induces Apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA acetate has anti-leukemic activity. nor-NOHA acetate improves liver ischemia-reperfusion injury. nor-NOHA acetate can used in study of tuberculosis, endothelial dysfunction, immunosuppression and metabolism .
    nor-NOHA acetate
  • HY-112885C
    nor-NOHA dihydrochloride
    5 Publications Verification

    Nω-Hydroxy-NOr-L-arginine dihydrochloride

    Apoptosis Arginase Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
    nor-NOHA dihydrochloride is a selective and reversible Arginase inhibitor. nor-NOHA dihydrochloride induces Apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA dihydrochloride has anti-leukemic activity. nor-NOHA dihydrochloride improves liver ischemia-reperfusion injury. nor-NOHA dihydrochloride can used in study of tuberculosis, endothelial dysfunction, immunosuppression and metabolism .
    nor-NOHA dihydrochloride
  • HY-18832

    Ephrin Receptor Cancer
    AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf .
    AWL-II-38.3
  • HY-12646A
    Rhosin
    Maximum Cited Publications
    40 Publications Verification

    Ras Apoptosis Cancer
    Rhosin is a potent, specific RhoA subfamily Rho GTPases inhibitor, which specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ~ 0.4 uM, and does not interact with Cdc42 or Rac1, nor the GEF, LARG. Rhosin induces cell apoptosis . Rhosin promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability .
    Rhosin
  • HY-12949
    ML204
    5+ Cited Publications

    TRP Channel Neurological Disease
    ML204 is a potent, selective TRPC4/TRPC5 channel inhibitor, with at least 19-fold selectivity against TRPC6 and no appreciable effect on all other TRP channels, nor on voltage-gated sodium, potassium, or Ca 2+ channels .
    ML204
  • HY-N6641
    Monascin
    2 Publications Verification

    Keap1-Nrf2 PPAR Inflammation/Immunology Cancer
    Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice). Monascin also exhibits anti-tumor-initiating activity and anti-inflammatory activity with oral administration. Monascin inhibits the activation of NOR 1 (an NO donor). Monascin is a Nrf2 activator and PPARγ agonist .
    Monascin
  • HY-D1266

    NO-red

    Fluorescent Dye Others
    RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm) .
    RB-OPD
  • HY-117040
    nor-Binaltorphimine
    5+ Cited Publications

    NOrbinaltorphimine; NOrBNI

    Opioid Receptor Neurological Disease
    nor-Binaltorphimine (Norbinaltorphimine; NorBNI) is a selective, long-acting competitive antagonist of the κ-opioid receptor. nor-Binaltorphimine blocks κ-opioid receptor-mediated analgesic effects, and inhibits butorphanol-induced changes in κ-opioid receptor binding kinetics, desensitization and down-regulation. nor-Binaltorphimine suppresses specific opioid withdrawal symptoms, precipitates withdrawal behaviors in butorphanol-dependent rats, and serves as a molecular probe for studying κ-opioid receptor-agonist interactions. nor-Binaltorphimine is applicable to research related to neurological disorders such as pain .
    nor-Binaltorphimine
  • HY-100903

    NOr-Binaltorphimine dihydrochloride; NOr-BNI dihydrochloride

    Opioid Receptor Neurological Disease
    Norbinaltorphimine dihydrochloride (nor-Binaltorphimine dihydrochloride; nor-BNI dihydrochloride) is a selective, long-acting competitive antagonist of the κ-opioid receptor. Norbinaltorphimine dihydrochloride blocks κ-opioid receptor-mediated analgesic effects, and inhibits butorphanol-induced changes in κ-opioid receptor binding kinetics, desensitization and down-regulation. Norbinaltorphimine dihydrochloride suppresses specific opioid withdrawal symptoms, precipitates withdrawal behaviors in butorphanol-dependent rats, and serves as a molecular probe for studying κ-opioid receptor-agonist interactions. Norbinaltorphimine dihydrochloride is applicable to research related to neurological disorders such as pain .
    Norbinaltorphimine dihydrochloride
  • HY-G0007
    Omeprazole sulfone
    2 Publications Verification

    Omeprazole sulphone

    Drug Metabolite Cytochrome P450 Aryl Hydrocarbon Receptor Inflammation/Immunology
    Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair .
    Omeprazole sulfone
  • HY-112885

    Nω-Hydroxy-NOr-L-arginine

    Apoptosis Arginase Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
    nor-NOHA is a selective and reversible arginase inhibitor. nor-NOHA induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA has anti-leukemic activity. nor-NOHA can used in study of endothelial dysfunction, immunosuppression and metabolism .
    nor-NOHA
  • HY-D1509

    Fluorescent Dye Others
    Phenazine ethosulfate is a cationic dye (Ex=390 nm, Em=530 nm) and an electron acceptor that can be used in dye-linked enzyme assays. Phenazine ethosulfate is an intermediate for detecting nitric oxide reducatase (Nors) activity with the presence of ascorbic acid .
    Phenazine ethosulfate
  • HY-153089
    GSK3-IN-3
    4 Publications Verification

    GSK-3 Mitophagy Neurological Disease
    GSK3-IN-3 is a mitophagy inducer, inducing Parkin-dependent mitophagy. GSK3-IN-3 is also a GSK-3 inhibitor with an IC50 value of 3.01 μM. GSK3-IN-3 is non-ATP nor substrate competitive and is neuroprotective against 6-OHDA .
    GSK3-IN-3
  • HY-23789

    2'-O-MOE-rG

    Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Others
    2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG) is a 2'-O-methoxyethyl-modified nucleoside analogue and an important intermediate in the synthesis of nucleic acid drugs. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA .
    2′-O-(2-Methoxyethyl)guanosine
  • HY-139899

    Taste Receptor Others
    S6821 is a TAS2R8 antagonist with IC50 value of 0.035 μM. S6821 is not found to be mutagenic or disruptive in vitro, nor is it found to induce micronucleus in bone marrow polychromatic erythrocytes in vivo .
    S6821
  • HY-126326

    Epoxide Hydrolase Metabolic Disease
    SWE101 (compound 22 b) is a potent soluble epoxide hydrolase (sEH)-P inhibitor with IC50s of 4 μM and 2.8 μM for human and rat sEH-P, respectively. SWE101 does not inhibit neither hydrolase nor phosphatase activity of the mouse sEH .
    SWE101
  • HY-W270810

    Nuclear Hormone Receptor 4A/NR4A Cancer
    NR4A agonist-1, a fatty acid mimetic (FAM), is a potent NR4A agonist. NR4A agonist-1 exhibits high agonist potency on NR4A receptors Nurr1, Nur77, and NOR-1, with EC50s of 0.09 μM, 0.04 μM, and 0.15 μM, respectively .
    NR4A agonist-1
  • HY-W722043

    O-456

    Drug Intermediate Dopamine Receptor Neurological Disease
    MFZ 2-13 (O-456) is an N-demethylated intermediate and N-nor-analogue of MFD 2-12. MFZ 2-13 inhibits dopamine uptake through the human dopamine receptor with an IC50 of 1.4 nM .
    MFZ 2-13
  • HY-W742532

    N-Ethyl-NOr-LSD

    5-HT Receptor Dopamine Receptor Neurological Disease
    ETH-LAD (N-Ethyl-nor-LSD) is an activator for 5-HT2A receptor with Ki of 5.1 nM. ETH-LAD exhibits affinity for dopamine receptor D1 and dopamine receptor D2 with Ki of 22.1 nM and 4.4 nM. ETH-LAD acts as psychoactive substance in rat model .
    ETH-LAD
  • HY-N15317

    β-Phocaecholic acid

    Drug Metabolite Metabolic Disease
    Phocaecholic acid (β-Phocaecholic acid) is a bile acid found in duck bile. Phocaecholic acid can be excreted into bile and partially decarboxylated to nor-chenodeoxycholic acid in rats. Phocaecholic acid is promising for research of bile acid metabolism and related diseases .
    Phocaecholic acid
  • HY-12949A
    ML204 hydrochloride
    5+ Cited Publications

    TRP Channel Neurological Disease
    ML204 hydrochloride is a novel, potent, selective TRPC4/TRPC5 channel inhibitor, with at least 19-fold selectivity against TRPC6 and no appreciable effect on all other TRP channels, nor on voltage-gated sodium, potassium, or Ca 2+ channels .
    ML204 hydrochloride
  • HY-W743888

    6-Allyl-6-NOr-LSD

    5-HT Receptor Dopamine Receptor Neurological Disease
    AL-LAD (6-Allyl-6-nor-LSD) is an activator for 5-HT2A receptor with Ki of 3.4-8.1 nM. AL-LAD exhibits affinity for dopamine receptor D1 and dopamine receptor D2 with absolute affinitiesK0.5 of 189 nM and 12.3 nM. AL-LAD acts as psychoactive substance in mouse model .
    AL-LAD
  • HY-N10851

    Others Others
    23-Nor-6-oxopristimerol is a phenolic dinor-triterpene .
    23-Nor-6-oxopristimerol
  • HY-114861

    Opioid Receptor Neurological Disease
    Nor-6α-Oxycodol is structurally similar to known opioids and is a metabolite of Oxycodone .
    Nor-6α-Oxycodol
  • HY-108357R

    L-6-Diazo-5-oxoNOrleucine (Standard); DON (Standard)

    Reference Standards Glutaminase Bacterial Influenza Virus Antibiotic Infection Cancer
    6-Diazo-5-oxo-L-nor-Leucine (Standard) is the analytical standard of 6-Diazo-5-oxo-L-nor-Leucine. This product is intended for research and analytical applications. 6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
    6-Diazo-5-oxo-L-nor-Leucine (Standard)
  • HY-B0132B

    MK-0366 (nicotinate)

    Bacterial Antibiotic Infection
    Norfloxacin nicotinate (MK-0366 nicotinate) is a fluoroquinolones antibiotic, an adduct of Norfloxacin (NOR) and nicotinic acid. Norfloxacin nicotinate has been widely used for replacing NOR in animal husbandry and fishery industry. Norfloxacin nicotinate can induce innate immune response at a high concentration .
    Norfloxacin (nicotinate)
  • HY-43711

    mAChR Neurological Disease
    Nor-benzetimide is a major metabolite of Benzetimide. Benzetimide is a mAChR antagonist with anticholinergic activity .
    Nor-benzetimide
  • HY-131896

    NOR4

    NO Synthase Cardiovascular Disease
    FR144420 (NOR4) is an orally active nitric oxide (NO)-releasing agent with vasodilatory and antiplatelet effects. FR144420 induces cGMP-mediated vasodilation and inhibits platelet aggregation. FR144420 is promising for research of cardiovascular diseases, particularly angina pectoris and coronary artery spasm .
    FR144420
  • HY-149812

    Bacterial Parasite Infection
    Efflux pump-IN-4 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-4 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-4 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model .
    AcrB-IN-4
  • HY-G0007R

    Omeprazole sulphone (Standard)

    Reference Standards Drug Metabolite Cytochrome P450 Aryl Hydrocarbon Receptor Infection Cancer
    Omeprazole sulfone (Standard) is the analytical standard of Omeprazole sulfone. This product is intended for research and analytical applications. Omeprazole sulfone (Omeprazole sulphone) is one of the major circulating metabolites of Omeprazole (HY-B0113) in vivo, and belongs to class 4 non-mutagenic impurities. Omeprazole sulfone does not bind to the aryl hydrocarbon receptor (AhR), nor does it induce the expression of CYP1A1 or CYP1A2. However, Omeprazole sulfone promotes the migration of gastric epithelial cells under basal conditions and reverses the inhibitory effect of Indomethacin (HY-14397) on cell migration. Omeprazole sulfone does not promote cell proliferation, nor does it upregulate COX-2 expression or activate signaling pathways such as ERK, P38 MAPK and PI3K. Omeprazole sulfone maintains basal ulcer healing under non-acid-dependent conditions and can be used in studies related to gastric ulcer repair .
    Omeprazole sulfone (Standard)
  • HY-N7040

    HSV Infection
    11-Deoxymogroside IIE is a cucurbitane glycoside, isolated from Siraitia grosvenorii fruits. 11-Deoxymogroside IIE has inhibitory effect against Epstein Barr virus (EBV-EA) activation induced by TPA, shows weak inhibitory effect on (+/-)-(E)-methyl1-2-[E-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR1), a NO donor .
    11-Deoxymogroside IIE
  • HY-172080

    Cannabinoid Receptor Neurological Disease
    (-)-7-Nor-7-carboxy cannabidiol is a phytocannabinoid metabolite. (-)-7-Nor-7-carboxy cannabidiol is a metabolite of Cannabidiol.
    (-)-7-Nor-7-carboxy cannabidiol
  • HY-157061S

    Isotope-Labeled Compounds Others
    7-Nor-7-carboxycannabidiol-d10 is deuterium-labeled 7-Nor-7-carboxycannabidiol .
    7-Nor-7-carboxycannabidiol-d10
  • HY-170047A

    11-NOr-9α-carboxy-HHC

    Cannabinoid Receptor Neurological Disease
    11-Nor-9(S)-carboxy-hexahydrocannabinol (11-Nor-9α-carboxy-HHC) is structurally similar to known phytocannabinoids .
    11-Nor-9(S)-carboxy-hexahydrocannabinol
  • HY-170047

    11-NOr-9β-carboxy-HHC

    Cannabinoid Receptor Neurological Disease
    11-Nor-9(S)-carboxy-hexahydrocannabinol (11-Nor-9β-carboxy-HHC) is structurally similar to known phytocannabinoids .
    11-Nor-9(R)-carboxy-hexahydrocannabinol
  • HY-143542S

    Isotope-Labeled Compounds Others
    Nor neostigmine-d6 is the deuterium labeled Nor neostigmine .
    Nor neostigmine-d6
  • HY-132435S

    Isotope-Labeled Compounds Others
    Nor Propranolol-d7 hydrochloride is the deuterium labeled Nor Propranolol hydrochloride .
    Nor Propranolol-d7 hydrochloride
  • HY-131101R

    Reference Standards Phosphodiesterase (PDE) Others
    Nor-Acetildenafil (Standard) is the analytical standard of Nor-Acetildenafil. This product is intended for research and analytical applications. Nor-Acetildenafil is an Acetildenafil derivative. Acetildenafil is a synthetic agent which acts as a phosphodiesterase inhibitor .
    Nor-Acetildenafil (Standard)
  • HY-168793

    Cannabinoid Receptor Neurological Disease
    (±)-9-Nor-9β-hydroxy Hexahydrocannabinol is structurally similar to known synthetic cannabinoids.
    (±)-9-Nor-9β-hydroxy Hexahydrocannabinol
  • HY-143665S

    Desphenethyl-W-18-d4

    Isotope-Labeled Compounds Others
    Nor-W-18-d4 is the deuterium labeled Nor-W-18 .
    Nor-W-18-d4
  • HY-146067

    Fungal Reactive Oxygen Species (ROS) Infection
    β-Nor-lapachone is a Candida glabrata antibiofilm agent. β-Nor-lapachone can stimulate ROS production, inhibits efflux activity, adhesion, biofilm formation and the metabolism of mature biofilms of Candida glabrata. β-Nor-lapachone has antifungal activity .
    β-Nor-lapachone
  • HY-168792

    Cannabinoid Receptor Metabolic Disease
    (±)-9-Nor-9α-hydroxy Hexahydrocannabinol is a cannabinoid-type compound that has strong cannabinoid-like activity in both dogs and mice .
    (±)-9-Nor-9α-hydroxy Hexahydrocannabinol
  • HY-N1713

    Others Neurological Disease
    29-Nor-20-oxolupeol, extracted from Impatiens basamina, reduces NO levels in LPS-activated murine microglial cells with an IC50 of 44.21 µM .
    29-Nor-20-oxolupeol
  • HY-19407

    PPAR Others
    Nor-LY-510929 is a compound whose development in the field of endocrinology and metabolism was stopped in 2005. Its specific active mechanism and application details are not described in detail based on the existing information.
    Nor-LY-510929
  • HY-N1607

    Others Others
    18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one is a compound isolated from the buds of Pinus banksiana Lamb .
    18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one
  • HY-N15709

    Bacterial Infection
    Nor-Rubrofusarin gentiobioside is a phenolic glycoside de-rubrofusarin that can be isolated from the seeds of Cassia tora. The same series of extracts of Nor-Rubrofusarin gentiobioside have antibacterial effects on Staphylococcus aureus strains .
    Nor-Rubrofusarin gentiobioside
  • HY-N1594

    Others Others
    15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid (compound 9) is a compound isolated from the roots of Chloranthus spicatus .
    15-Nor-14-oxolabda-8(17),12E-Diene-18-oic acid

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: