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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
NOD2 antagonist 1
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "NOD2 antagonist 1" in MCE Product Catalog:
Research Areas:
NOD2 antagonist 1 is a selective NOD2 antagonist with an IC50 of 5.23 μM. NOD2 antagonist 1 acts directly on the NOD2 protein, downregulates the secretion of pro-inflammatory cytokines such as IL-8 and TNF-α, and inhibits the synergistic cross-response of inflammation mediated by NOD2 and TLR4. NOD2 antagonist 1 can be used in studies related to immunity and inflammation .
Cat. No.: HY-146034
CAS No.: 2704623-69-6
Target:
Research Areas:
NOD1/2 antagonist-1 (compound 36b) is a potent NOD1/2 (nucleotide-binding
oligomerization domain-like receptor 1/2) dual antagonist, with IC50 values of 1.13 (NOD1) and 0.77 μM (NOD2), respectively. NOD1/2 antagonist-1 has a acceptable T1/2 (67.6 min). NOD1/2 antagonist-1 (compound 36b) can improve the antitumor efficacy of Paclitaxel (PTX) .
Cat. No.: HY-163274
CAS No.: 3030588-37-2
Target:
Research Areas:
NOD1 antagonist-1 (compound 37) exhibits an antagonistic activity towards NOD1 and a weak NOD1/NOD2 selectivity, with IC50s of 9.18 μM and 20.8 μM, respectively .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
