14 Results for "

Nuclear receptor Nur77

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "Nuclear receptor Nur77" in MCE Product Catalog:

18
18 Publications Verification
Cat. No.: HY-N2148
CAS No.: 321661-62-5
Synonyms: Csn-B; Dothiorelone G
Cytosporone B (Csn-B; Dothiorelone G) is a naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with an EC50 of 0.278 nM.
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2
2 Cited Publications
Cat. No.: HY-P1624
CAS No.: 197922-42-2
Synonyms: ALX-0600
Teduglutide (ALX-0600) is an analog of human glucagon like peptide-2 (GLP-2). Teduglutide can activate the expression of nuclear receptor subfamily 4 group a member 1 (NR4a1)/nur77 and intestinal FXR signaling in human hepatic stellate cells, thereby improving liver inflammation and fibrosis in mice with sclerosing cholangitis. Teduglutide can alleviate intestinal dysfunction in mice, improve lung injury, alleviate obesity related neuroinflammation and cell apoptosis .
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1
1 Cited Publications
Cat. No.: HY-111492
CAS No.: 33985-68-1
Purity:  99.41%
Research Areas:  

Cancer

DIM-C-pPhOCH3 is a Nur77 agonist. Nerve growth factor-induced Bα (NGFI-Bα, Nur77) is an orphan nuclear receptor.
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Cat. No.: HY-P1624S1
Synonyms: ALX-0600-Leu(13C6,15N) sodium
Teduglutide-Leu( 13C6, 15N) (ALX-0600-Leu( 13C6, 15N)) sodium is the 13C- and 15N-labeled Teduglutide (HY-P1624). Teduglutide (ALX-0600) is an analog of human glucagon like peptide-2 (GLP-2). Teduglutide can activate the expression of nuclear receptor subfamily 4 group a member 1 (NR4a1)/nur77 and intestinal FXR signaling in human hepatic stellate cells, thereby improving liver inflammation and fibrosis in mice with sclerosing cholangitis. Teduglutide can alleviate intestinal dysfunction in mice, improve lung injury, alleviate obesity related neuroinflammation and cell apoptosis .
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Cat. No.: HY-P1624A
Synonyms: ALX-0600 TFA
Teduglutide TFA is a dipeptidyl peptidase IV resistant glucagon-like peptide 2 (GLP-2) analogue. Teduglutide TFA can activate the expression of nuclear receptor subfamily 4 group a member 1 (NR4a1)/nur77 and intestinal FXR signaling in human hepatic stellate cells, thereby improving liver inflammation and fibrosis in mice with sclerosing cholangitis. Teduglutide TFA can alleviate intestinal dysfunction in mice, improve lung injury, alleviate obesity related neuroinflammation and cell apoptosis .
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Cat. No.: HY-N2148R
CAS No.: 321661-62-5
Synonyms: Csn-B (Standard); Dothiorelone G (Standard)
Cytosporone B (Standard) is the analytical standard of Cytosporone B. This product is intended for research and analytical applications. Cytosporone B (Csn-B; Dothiorelone G) is a naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with an EC50 of 0.278 nM.
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Cat. No.: HY-169907
CAS No.: 2891984-12-4
Anticancer agent 258 is an imidazo [1,2-B][1,2,4] triazol derivative. Anticancer agent 258 regulates the activity of nuclear receptors. Anticancer agent 258 has an EC50 of 63 nM against Nurr in N2A cells. Anticancer agent 258 has IC50 of 0.1 pM for Nur77 in HEK293 cells. Anticancer agent 258 can be used in the study of cancer, metabolic diseases and neurological disorders .
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Cat. No.: HY-P1624S
Synonyms: ALX-0600-Ala(13C3,15N) sodium
Teduglutide-Ala( 13C3, 15N) (ALX-0600-Ala( 13C3, 15N)) sodium is the 13C- and 15N-labeled Teduglutide (HY-P1624). Teduglutide (ALX-0600) is an analog of human glucagon like peptide-2 (GLP-2). Teduglutide can activate the expression of nuclear receptor subfamily 4 group a member 1 (NR4a1)/nur77 and intestinal FXR signaling in human hepatic stellate cells, thereby improving liver inflammation and fibrosis in mice with sclerosing cholangitis. Teduglutide can alleviate intestinal dysfunction in mice, improve lung injury, alleviate obesity related neuroinflammation and cell apoptosis .
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Cat. No.: HY-111492R
CAS No.: 33985-68-1
DIM-C-pPhOCH3 (Standard) is the analytical standard of DIM-C-pPhOCH3 (HY-111492). This product is intended for research and analytical applications. DIM-C-pPhOCH3 is a Nur77 agonist. Nerve growth factor-induced Bα (NGFI-Bα, Nur77) is an orphan nuclear receptor.
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Cat. No.: HY-P81717
Synonyms: NR4A1; GFRP1; HMR; NAK1; Nuclear receptor subfamily 4 group A member 1; Early response protein NAK1; Nuclear hormone receptor Nur/77; Nur77; Orphan Nuclear receptor HMR; Orphan Nuclear receptor TR3; ST-59; Testicular receptor 3

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P81717A
Synonyms: NR4A1; GFRP1; HMR; NAK1; Nuclear receptor subfamily 4 group A member 1; Early response protein NAK1; Nuclear hormone receptor Nur/77; Nur77; Orphan Nuclear receptor HMR; Orphan Nuclear receptor TR3; ST-59; Testicular receptor 3

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P7S1786
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NR4A1; Orphan Nuclear receptor HMR; Prev. GFRP1; Testicular receptor 3; Prev. HMR; ST-59; NAK-1; Nuclear receptor Subfamily 4, Group A, Member 1; NGFIB; Growth Factor-Inducible Nuclear Protein N10; Nur77; Steroid receptor TR3; TR3; TR3 Orphan receptor; N1
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P71765
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NR4A2; NGFI-B/Nur77 Beta-Type Transcription Factor Homolog; Prev. NurR1; Nur Related Protein-1, Human Homolog Of; TINur; Orphan Nuclear receptor NR4A2 Isoform 1; NOT; Orphan Nuclear receptor NR4A2 Isoform 2; HZF-3; Intermediate-Early receptor Protein; RNR
Species:  
Human
Source:  
P. pastoris
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Cat. No.: HY-180786
CAS No.: 3085711-53-8
DdBIC is a pyroptosis inducer. DdBIC binds to Nur77 and triggers its translocation to mitochondria, activates SDHA to deplete succinyl-CoA, disrupts heme homeostasis, induces electron leakage, and elicits mitochondrial ROS production. DdBIC induces mitochondrial ROS that oxidatively activates OMA1, promotes OPA1 cleavage and its release into the cytoplasm, activates the integrated stress response via PERK, and ultimately activates granzyme B to cleave GSDMC. DdBIC can be used for the study of melanoma .
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