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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
41 Results for "
OSM
" in MedChemExpress (MCE) Product Catalog:
Products (41)
41 Results for "OSM" in MCE Product Catalog:
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Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage, and induces apoptosis via a p53-dependent mitochondrial signaling pathway .
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Cat. No.: HY-175465
CAS No.: 3108487-29-9
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SMI-10B13 is an Oncostatin M (OSM) inhibitor with a KD of 6.6 μM. SMI-10B13 inhibits OSM-mediated STAT3 phosphorylation in T47D and MCF-7 cell lines (IC50 = 136 and 164 nM, respectively). SMI-10B13 shows anti-tumor effect in human breast cancer mice models .
Cat. No.: HY-162238
CAS No.: 2650846-59-4
OSM-S-106 is a pro-inhibitor and that inhibition of PfAsnRS occurs via enzyme-mediated production of an Asn-OSM-S-106 adduct. OSM-S-106 inhibits protein translation and activates the amino acid starvation response. OSM-S-106 exhibits selective activity against Plasmodium blood and liver stages and low intrinsic clearance by human microsomes .
Cat. No.: HY-148693
CAS No.: 1689690-20-7
Synonyms: NSC642624
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OSM-SMI-8 (NSC642624) is a potent OSM (oncostatin M) antagonist. OSM-SMI-8 has the potential for the research of cancer .
Cat. No.: HY-P991333
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Cat. No.: HY-P991051
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Cat. No.: HY-148695B
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ADR58 sodium is a highly potent and selective human oncostatin M (OSM) antagonist, which can prevent the binding of OSM to the gp130 receptor and specifically antagonize OSM-mediated signaling. ADR58 sodium can be used in the research of rheumatoid arthritis related diseases .
Cat. No.: HY-148692A
CAS No.: 2502294-55-3
(E/Z)-OSM-SMI-10B a derivative of OSM-SMI-10. (E/Z)-OSM-SMI-10B significantly reduces OSM-induced STAT3 phosphorylation in cancer cells upon co-incubation with OSM (Oncostatin M) .
Cat. No.: HY-148693A
Synonyms: (E/Z)-NSC642624
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(E/Z)-OSM-SMI-8 is the racemate of OSM-SMI-8 (HY-148693). OSM-SMI-8 is the antagonist for OSM (oncostatin M), that exhibits the potential in anti-cancer research .
Cat. No.: HY-148695C
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ADR58 sodium is a highly potent and selective human oncostatin M (OSM) antagonist, which can prevent the binding of OSM to the gp130 receptor and specifically antagonize OSM-mediated signaling. ADR58 sodium can be used in the research of rheumatoid arthritis related diseases .
Cat. No.: HY-RS09850
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OSM Human Pre-designed siRNA Set A contains three designed siRNAs for OSM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22979
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Osm Rat Pre-designed siRNA Set A contains three designed siRNAs for Osm gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
