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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
64 Results for "
P38 mitogen-activated protein kinase
" in MedChemExpress (MCE) Product Catalog:
Products (64)
64 Results for "P38 mitogen-activated protein kinase" in MCE Product Catalog:
4
3
3 Cited Publications
Cat. No.: HY-P80842
Synonyms: MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein
2
Research Areas:
Skepinone-L (CBS3830), a chemical probe, is a selective p38 mitogen-activated protein kinase inhibitor.
2
2 Cited Publications
Cat. No.: HY-18758
CAS No.: 868612-83-3
Target:
Research Areas:
IN-1130 is a highly selective transforming growth factor-β type I receptor kinase (ALK5) inhibitor with an IC50 of 5.3 nM for ALK5-mediated Smad3 phosphorylation. IN-1130 inhibits ALK5 phosphorylation of casein (IC50=36 nM) and p38α mitogen-activated protein kinase (IC50=4.3 μM). IN-1130 suppresses renal fibrosis in obstructive nephropathy and blocks breast cancer lung metastasis .
2
2 Cited Publications
Cat. No.: HY-P80996
Synonyms: CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A, MAPK14, mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, MAP kinase MXI2, MAX-interacting protein 2, mitogen-activated protein kinase P38 alpha, Stress-activated protein kinase 2a, CSAID-binding protein, MAP kinase P38 alpha, SAPK2a
2
2 Cited Publications
Cat. No.: HY-P80776
Synonyms: MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein
2
2 Cited Publications
Cat. No.: HY-P80777
Synonyms: MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein
1
1 Cited Publications
Category:
1
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-14974
CAS No.: 449811-92-1
Target:
Research Areas:
R 1487 is an orally active and highly selective p38α mitogen-activated protein kinase inhibitor. R 1487 can be used in the study of rheumatoid arthritis .
1
1 Cited Publications
Cat. No.: HY-P80776A
Synonyms: P38 (phospho T180 + Y182); p-P38 (phospho T180 + Y182); P38 (phospho T180/Y182); CSAID Binding protein 1; CSAID binding protein; CSAID-binding protein; Csaids binding protein; CSBP 1; CSBP 2; CSBP; CSBP1; CSBP2; CSPB 1; CSPB1; Cytokine suppressive anti inflammatory drug binding protein; Cytokine suppressive anti-inflammatory drug-binding protein; EXIP; MAP kinase 14; MAP kinase MXI2; MAP kinase P38 alpha; MAPK 14; MAPK14; MAX interacting protein 2; MAX-interacting protein 2; mitogen activated protein kinase 14; mitogen activated protein kinase P38 alpha; mitogen-activated protein kinase 14; mitogen-activated protein kinase P38 alpha; MK14_HUMAN; Mxi 2; Mxi2; P38 ALPHA; P38; P38 MAP kinase; P38 MAPK; P38 mitogen activated protein kinase; P38ALPHA; P38alpha Exip; PRKM14; PRKM15; RK; SAPK 2A; SAPK2A; Stress activated protein kinase 2A.
1
1 Cited Publications
Cat. No.: HY-P73335
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MAPK14; SAPK2A; Prev. CSBP1; Cytokine Suppressive Anti-Inflammatory Drug Binding protein; Prev. CSBP2; Cytokine Suppressive Anti-Inflammatory Drug-Binding protein; Prev. CSPB1; P38 mitogen activated protein kinase; mitogen-activated protein kinase P38 Alp
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P80213
Synonyms: CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A, MAPK14, mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, MAP kinase MXI2, MAX-interacting protein 2, mitogen-activated protein kinase P38 alpha, Stress-activated protein kinase 2a, CSAID-binding protein, MAP kinase P38 alpha, SAPK2a
Synonyms: ATI-450; CDD-450
Target:
Research Areas:
Zunsemetinib (CDD-450) is an orally active and selective p38α mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway inhibitor. Zunsemetinib can be used for the research of immuno-inflammatory diseases .
Cat. No.: HY-N4119
CAS No.: 13241-32-2
Category:
other families Flavonoids Flavonones Phenols Polyphenols Plants
Cat. No.: HY-P10954
CAS No.: 197295-74-2
Research Areas:
Meptyldinocap (2,4-DNOPC) is a fungicide and cytotoxic agent that acts against powdery mildew. Meptyldinocap upregulates the phosphorylation levels of ERK1/2, JNK and p38. Meptyldinocap induces apoptosis and endoplasmic reticulum stress, disrupts calcium homeostasis, inhibits cell proliferation and migration, downregulates the expression of proliferation- and pregnancy-related genes, and triggers mitochondrial dysfunction. Meptyldinocap can be used in studies related to powdery mildew and implantation failure .
Cat. No.: HY-119715
CAS No.: 486414-35-1
Research Areas:
AG-012986 is a pan-CDK inhibitor with Ki values of 44 nM (CDK1), 9.2 nM (CDK4), 94 nM (CDK2), and IC50 values of 22 nM (CDK5), 4 nM (CDK9). AG-012986 causes apoptosis of T-cells by targeting upstream kinases in the p38 Mitogen-activated protein kinase (MAPK) pathway and impairing cellular survival. AG-012986 induces cell cycle arrest, retinoblastoma protein hypophosphorylation, and reduces Ki-67 expression. AG-012986 exerts antiproliferative activity in tumor cells, demonstrates antitumor efficacy in human xenograft models, and causes retinal and peripheral neurotoxicity, plus immune cell toxicity. AG-012986 can be used for the research of colon carcinoma, non-small cell lung carcinoma, lung carcinoma, breast carcinoma, ovarian tumor, pancreatic carcinoma, osteosarcoma, lymphoma, leukemia, retinotoxicity .
Cat. No.: HY-N5073
CAS No.: 178468-00-3
Synonyms: 4''-O-Glucosylvitexin
Cat. No.: HY-117068
CAS No.: 478288-90-3
Synonyms: (R,E)-Bromoenol lactone
Target:
Research Areas:
(R)-Bromoenol lactone ((R,E)-Bromoenol lactone) is an isomer of Bromoenol lactone (HY-107411). (R)-Bromoenol lactone acts as a selective inhibitor of microsomal calcium-independent phospholipase A2γ (iPLA2γ). (R)-Bromoenol lactone induces mild activation of p38 mitogen-activated protein kinase in prostate cancer cells, resulting in slight increases in the expressions of phosphorylated p53, total p53 and p21. (R)-Bromoenol lactone is applicable to prostate cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
