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PGF2α-isopropyl ester

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-106037
    PGF2α-isopropyl ester

    		Prostaglandin Receptor Others
    PGF2α-isopropyl ester is a Prostaglandin F2α (HY-12956) derivative, which is active in lowering the intraocular pressure (IOP) through increased uveoscleral outflow of aqueous humor. PGF2α-isopropyl ester causes side effects of conjunctival hyperemia and ocular irritation .
    PGF2α-isopropyl ester
  • HY-116161A
    17-Phenyl trinor PGF2α isopropyl ester

    		Prostaglandin Receptor Metabolic Disease
    17-Phenyl trinor PGF2α isopropyl ester is a FP receptor agonist and intraocular pressure-lowering agent. 17-Phenyl trinor PGF2α isopropyl ester induces iris sphincter contraction, reduces intraocular pressure and pupil diameter, causes no ocular irritation, and only leads to mild conjunctival hyperemia. 17-Phenyl trinor PGF2α isopropyl ester is applicable to relevant research on glaucoma .
    17-Phenyl trinor PGF2α isopropyl ester
  • HY-116161
    Bimatoprost isopropyl ester

    		Drug Intermediate Cardiovascular Disease Others
    15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.
    Bimatoprost isopropyl ester
  • HY-118294
    15-OH Tafluprost

    16-Phenoxy tetranor prostaglandin F2α isopropyl ester; 16-Phenoxy tetranor PGF2α isopropyl ester

    		 Prostaglandin Receptor Cardiovascular Disease
    15-OH Tafluprost, a prostaglandin F2a (PGF2a) analog, relieves endothelin-1 (ET-1)-induced optic nerve head (ONH) blood flow impairment and ET-1-induced contraction of isolated ciliary artery segments .
    15-OH Tafluprost
  • HY-175105
    17-Phenoxy trinor prostaglandin F2α isopropyl ester

    17-Phenoxy-PGF2α isopropyl ester

    		 Drug Derivative Endocrinology
    17-Phenoxy trinor prostaglandin F2α isopropyl ester is a PGF2α (HY-12956) analog. PGF2α is an orally active agonist of the PGF receptor (FP receptor). PGF2α plays a key role in labor and delivery.
    17-Phenoxy trinor prostaglandin F2α isopropyl ester
  • HY-116502
    13,14-Dihydro-15-keto prostaglandin F2α isopropyl ester

    13,14-Dihydro-15-keto PGF2α isopropyl ester

    		 Biochemical Assay Reagents Others
    13,14-Dihydro-15-keto prostaglandin F2α isopropyl ester is an esterified form of 13,14-dihydro-15-keto PGF2α.
    13,14-Dihydro-15-keto prostaglandin F2α isopropyl ester

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