22 Results for "

Pancreatic polypeptide

" in MedChemExpress (MCE) Product Catalog:
Products (22)

22 Results for "Pancreatic polypeptide" in MCE Product Catalog:

Cat. No.: HY-P4060
CAS No.: 59763-91-6
Research Areas:  

Metabolic Disease Endocrinology

Pancreatic polypeptide is a peptide secreted by the endocrine PP cells of the pancreas that regulates pancreatic secretory activity and also affects hepatic glycogen stores and gastrointestinal secretion .
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17
17 Publications Verification
Cat. No.: HY-P1156
CAS No.: 11070-73-8
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease Endocrinology

Insulin cattle is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells. Insulin cattle has often been used as growth supplement in culturing cells.
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3
3 Cited Publications
Cat. No.: HY-P10138
CAS No.: 1884226-05-4
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Human GIP(3-30), amide is a high affinity antagonist of the human GIP receptor in vitro. Human GIP(3-30), amide has potential anti-obesity and anti-diabetic effects .
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3
3 Cited Publications
Cat. No.: HY-P10138A
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Human GIP(3-30), amide TFA is the TFA salt form of human GIP(3-30), amide (HY-P10138). Human GIP(3-30), amide TFA is a high affinity antagonist of the human GIP receptor in vitro. Human GIP(3-30), amide TFA has potential anti-obesity and anti-diabetic effects .
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2
2 Cited Publications
Cat. No.: HY-P10769
CAS No.: 2209854-03-3
Target:  

AMPK Apoptosis

Research Areas:  

Metabolic Disease

MOTS-c (mouse) is a mitochondrial-derived polypeptide that can be used to regulates pancreatic cell function. MOTS-c (mouse) reduces insulin secretion and expression in INS-1E cells, and enhances glucagon secretion and expression in αTC-1 cells. MOTS-c (mouse) decreases the apoptosis in INS-1E and αTC-1. MOTS-c (mouse) counteracts diet-induced obesity and insulin resistance through AMPK activation .
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Cat. No.: HY-129046C
Synonyms: Ribonuclease B, Bovine Pancreas
Research Areas:  

Endocrinology Cancer

RNase A (Bovine pancreatic RNase) is a widely used Endonuclease in DNA purification by specifically hydrolyzing cytosine or uracil residues of RNA. RNase A degrades the RNA in the RNA/DNA duplex. RNase A catalyses the breakdown of 3',5'-phosphodiester linkages of single stranded RNA. RNase A family members in organisms are tightly involved in various physiological and pathological processes including cell growth and development, proliferation, differentiation and migration. Dysregulation of RNase A activity or expression level is closely related to pancreatic, ovarian, bladder and thyroid cancer. RNase A has tumor cell-killing ability. RNase B, Bovine Pancreas (Ribonuclease B, Bovine Pancreas) is the N-glycosylated form of RNase A. RNase B, Bovine Pancreas can promote the folding of polypeptide chains and play a role similar to molecular chaperones .
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Cat. No.: HY-P10735
CAS No.: 181591-59-3
Synonyms: Gastric inhibitory polypeptide(mouse); GIP(1-42) (mouse)
Target:  

Lipase Apoptosis

Research Areas:  

Metabolic Disease

GIP (Gastric inhibitory polypeptide) (mouse) is a gastrointestinal hormone that is secreted by the intestinal K cells, and also expressed in and secreted from pancreatic islets. GIP (mouse) promotes insulin secretion from pancreatic β cells via the G-protein-coupled GIP receptor (GIPR). GIP (mouse) promotes pancreatic β cell proliferation and inhibits apoptosis. GIP (mouse) also exerts direct lipogenic effects on adipose tissue .
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Cat. No.: HY-P1070A
Synonyms: DAP amide, human TFA
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Amylin, amide, human TFA, a 37-amino acid polypeptide, is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin, amide, human TFA inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent .
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Cat. No.: HY-P0199
CAS No.: 75976-10-2
Synonyms: Human Pancreatic polypeptide
Research Areas:  

Metabolic Disease Endocrinology

Pancreatic Polypeptide, human is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.
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Cat. No.: HY-P1070
CAS No.: 122384-88-7
Synonyms: DAP amide, human
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Amylin, amide, human, a 37-amino acid polypeptide, is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin, amide, human inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent .
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Cat. No.: HY-P1532
CAS No.: 90419-12-8
Synonyms: Rat Pancreatic polypeptide
Pancreatic Polypeptide, rat (Rat pancreatic polypeptide) is a rat-derived Pancreatic Polypeptide. Pancreatic Polypeptide is a preferential agonist of NPYR4. Pancreatic Polypeptide, rat protects cells against Streptozotocin (HY-13753)-induced DNA damage. Pancreatic Polypeptide, rat inhibits glucose-stimulated insulin secretion. Pancreatic Polypeptide, rat (TFA) can be used in diabetes-related research .
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Cat. No.: HY-P5074
CAS No.: 1132745-52-8
Target:  

GCGR

Research Areas:  

Metabolic Disease

GRPP (human) is a 30 amino acid Gcg-derived peptide. GRPP (human) causes slight increases in plasma insulin and decreases in plasma glucagon. GRPP (human) does not affect insulin secretion in rat islets .
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Cat. No.: HY-165125
CAS No.: 1175940-86-9
Research Areas:  

Metabolic Disease

(S)-VU0637120 is a Y4R antagonist that effectively reduces the binding response of its endogenous ligand, pancreatic polypeptide (PP), on Y4R, with an IC50 value of 2.7 μM. (S)-VU0637120 binds to the allosteric site of Y4R, which is located in the core region of the Y4R transmembrane structure, near the binding pocket of pancreatic polypeptide (PP), with a KB value of 300-400 nM. (S)-VU0637120 holds potential for research in the field of metabolic diseases .
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Cat. No.: HY-P4060A
Research Areas:  

Others

Pancreatic polypeptide TFA is a neuropeptide Y (NPY) Y4/Y5 receptor agonist.
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Cat. No.: HY-P1537
CAS No.: 179986-89-1
Research Areas:  

Metabolic Disease Endocrinology

Pancreatic Polypeptide, bovine, a 36-amino acid, straight chain polypeptide derived primarily from the pancreas, inhibits secretin- and cholecystokinin-stimulated pancreatic secretion; Pancreatic Polypeptide, bovine acts as an agonist of NPY receptor, with high affinity at NPYR4.
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Cat. No.: HY-P1871A
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Amylin (IAPP), feline TFA is a 37-amino acid polypeptide from feline. Amylin (IAPP), feline TFA is one of the major secretory products of β-cells of the pancreatic islets. Amylin (IAPP), feline TFA is a regulatory peptide, which inhibits insulin and glucagon secretion .
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Cat. No.: HY-P1871
CAS No.: 213779-12-5
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Amylin (IAPP), feline is a 37-amino acid polypeptide from feline. Amylin (IAPP), feline is one of the major secretory products of β-cells of the pancreatic islets. Amylin (IAPP), feline is a regulatory peptide, which inhibits insulin and glucagon secretion .
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Cat. No.: HY-P71062
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPY; Pancreatic polypeptide Prohormone; Pancreatic polypeptide; PH; PNP; Pancreatic Prohormone; Pancreatic polypeptide Y; Obinepitide; Prepro-PP (PreproPancreatic polypeptide); PP
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-174547
Target:  

mRNA

Research Areas:  

Metabolic Disease

Human PDX1 mRNA encodes the human pancreatic and duodenal homeobox 1 (PDX1) protein, a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. PDX1 may be involved in the early development of the pancreas. It also plays a major role in glucose-dependent regulation of insulin gene expression.
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Cat. No.: HY-P87020
Synonyms: Pancreatic polypeptide antibody; Pancreatic polypeptide Y antibody; Pancreatic prohormone antibody; PNP antibody; PP antibody; PPY antibody; prepro-PP (preproPancreatic polypeptide) antibody;

Host:  

Rabbit

Application:  

IHC-P, IHC-F, IF-Tissue, mIHC

Reactivity:  

Mouse, Rat

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