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Phenolic Hydroxyl Groups

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By Targets:	Biochemical Assay Reagents (4) Drug Intermediate (1) Drug Metabolite (4) Endogenous Metabolite (2) Lipase (1) PDI (1) Phosphatase (1) Reference Standards (4) Tyrosinase (2) UGT (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (6) Metabolic Disease (2)

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W127711

Fast Blue B Salt, Dye content ~95%	Phosphatase Lipase	Metabolic Disease Inflammation/Immunology
Fast Blue B Salt, Dye content ~95% is a diazo dye, primarily used as a chromogenic substrate in biochemical analysis. Fast Blue B Salt, Dye content ~95% is the coupling agent for the histochemical demonstration of proteases. Fast Blue B Salt, Dye content ~95% can be used for the detection of acid phosphatase in Clostridium perfringens, and also for the determination of lipase activity. Fast Blue B Salt, Dye content ~95% reacts directly with the active hydroxyl groups in phenolic compounds to determine the content of phenolic substances .

HY-Y0801

2,6-Dihydroxybenzoic acid	Drug Metabolite	Others
2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

HY-G0004

Acetaminophen metabolite 3-hydroxy-acetaminophen 3-Hydroxyacetaminophen	Drug Metabolite	Inflammation/Immunology
Acetaminophen metabolite 3-hydroxy-acetaminophen (3-Hydroxyacetaminophen) is a non-toxic metabolite and antioxidant of acetaminophen (HY-66005) with free radical scavenging activity. Acetaminophen metabolite 3-hydroxy-acetaminophen can reduce oxidative damage by exerting electron donation ability and antioxidant activity through phenolic hydroxyl groups. 3-hydroxy-acetaminophen can be used to study the toxicity mechanism and drug metabolism of acetaminophen .

HY-Y1374

Benzoic anhydride	Biochemical Assay Reagents	Others
Benzoic anhydride is a catalyst that can be used for organic synthesis reactions. Benzoic anhydride is used as a chemical titration reagent for selective quantification and deactivation of phenolic hydroxyl groups on the surface of carbon nanotubes .

HY-W017092

1,2,3-Trimethoxybenzene	Drug Intermediate	Others
1,2,3-Trimethoxybenzene is a model compound of lignin. 1,2,3-Trimethoxybenzene can potentially serve as a biomarker for certain foods due to its presence in tea. 1,2,3-Trimethoxybenzene can be used as a drug intermediate for synthesizing 2,6-dimethoxy-1,4-benzoquinone (HY-N1677) .

HY-W007671

H-Tyr-OMe 1 Publications Verification	Endogenous Metabolite Tyrosinase	Others
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

HY-W007671R

H-Tyr-OMe (Standard)	Reference Standards Endogenous Metabolite Tyrosinase	Others
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

HY-Y1374R

Benzoic anhydride (Standard)	Biochemical Assay Reagents Reference Standards	Others
Benzoic anhydride (Standard) is the analytical standard of Benzoic anhydride. This product is intended for research and analytical applications. Benzoic anhydride is a catalyst that can be used for organic synthesis reactions. Benzoic anhydride is used as a chemical titration reagent for selective quantification and deactivation of phenolic hydroxyl groups on the surface of carbon nanotubes .

HY-Y0801R

2,6-Dihydroxybenzoic acid (Standard)	Reference Standards Drug Metabolite	Others
2,6-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,6-Dihydroxybenzoic acid (HY-Y0801). This product is used for research and analytical applications. 2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

HY-G0004R

Acetaminophen metabolite 3-hydroxy-acetaminophen (Standard) 3-Hydroxyacetaminophen (Standard)	Reference Standards Drug Metabolite	Inflammation/Immunology
Acetaminophen metabolite 3-hydroxy-acetaminophen (3-Hydroxyacetaminophen) (Standard) is the analytical standard of Acetaminophen metabolite 3-hydroxy-acetaminophen (HY-G0004). This product is intended for research and analytical applications. Acetaminophen metabolite 3-hydroxy-acetaminophen is a non-toxic metabolite and antioxidant of acetaminophen (HY-66005) with free radical scavenging activity. Acetaminophen metabolite 3-hydroxy-acetaminophen can reduce oxidative damage by exerting electron donation ability and antioxidant activity through phenolic hydroxyl groups. 3-hydroxy-acetaminophen can be used to study the toxicity mechanism and drug metabolism of acetaminophen .

HY-N15727

2,5-Dimethylchromone-7-O-β-D-glucopyranoside	Others	Inflammation/Immunology
2,5-Dimethylchromone-7-O-β-D-glucopyranoside is an orally active chromone glycoside found in the underground parts of Rheum australe. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside shows a DPPH radical scavenging activity with an IC₅₀ value of 66.9 μM. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside scavenges free radicals by providing hydrogen atoms through phenolic hydroxyl groups, inhibiting lipid peroxidation. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside is promising for research of oxidative stress-related diseases such as inflammation and skin diseases .

HY-W413662

4-((4-Methoxybenzyl)oxy)butan-1-ol	Biochemical Assay Reagents	Others
4-[(4-Methoxyphenyl)methoxy]butan-1-ol is a compound with a methyl phenol group and a butanol tail. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

HY-W015811

3-N-Propylphenol	PDI	Metabolic Disease Inflammation/Immunology Cancer
3-N-Propylphenol is a small phenolic derivative containing a hydroxyl aryl group that competitively inhibits the binding of the peptide to pancreatic-specific protein disulfide isomerase (PDIp). 3-Propylphenol can be used for research on pancreatic-related diseases .

HY-E71131

(S)-Stylopine synthase	Biochemical Assay Reagents	Others
(S)-Stylopine synthase (EC 1.14.21.1) catalyzes an oxidation reaction that does not introduce oxygen into the product. (S)-Stylopine synthase (EC 1.14.21.1) forms a second methylenedioxy bridge in the protoberberine alkaloid stylopine by oxidatively cyclizing cheilanthifoline with adjacent phenolic hydroxyl and methoxy groups.

HY-W006081

3-Methyl-2-nitrophenol	UGT	Others
3-Methyl-2-nitrophenol is a UDP-glucuronyltransferase (EC 2.4.1.17) acceptor substrate that can be confirmed to undergo glucuronidation catalyzed by the enzyme to form a glucuronide conjugate. 3-Methyl-2-nitrophenol functions as a substrate for conjugation, with glucuronidation forming a glucuronide conjugate that eliminates the parent compound’s characteristic yellow color. 3-Methyl-2-nitrophenol has higher lipid solubility that contributes to high glucuronidation conversion rate, and exhibits lower absorbance at 340 nm to act as a less interfering substrate for the NADH-NAD ⁺-linked UDP-glucuronyltransferase assay .

HY-N17138

threo-1-(4-Hydroxyphenyl)-1-methoxy-2,3-propanediol	Others	Inflammation/Immunology Cancer
threo-1-(4-Hydroxyphenyl)-1-methoxy-2,3-propanediol is an aromatic propanediol phenolic derivative containing methoxy and hydroxyl groups. It can be naturally extracted from the dried aerial parts of Abies delavayi Franch. var. delavayi (Cangshan fir) from Dali, Yunnan, China. This source plant produces anti-inflammatory and anti-tumor active components .

Cat. No.	Product Name	Type

HY-W127711

Fast Blue B Salt, Dye content ~95%	Fluorescent Dyes
Fast Blue B Salt, Dye content ~95% is a diazo dye, primarily used as a chromogenic substrate in biochemical analysis. Fast Blue B Salt, Dye content ~95% is the coupling agent for the histochemical demonstration of proteases. Fast Blue B Salt, Dye content ~95% can be used for the detection of acid phosphatase in Clostridium perfringens, and also for the determination of lipase activity. Fast Blue B Salt, Dye content ~95% reacts directly with the active hydroxyl groups in phenolic compounds to determine the content of phenolic substances .

Fast Blue B Salt, Dye content ~95%

Fluorescent Dyes

Fast Blue B Salt, Dye content ~95% is a diazo dye, primarily used as a chromogenic substrate in biochemical analysis. Fast Blue B Salt, Dye content ~95% is the coupling agent for the histochemical demonstration of proteases. Fast Blue B Salt, Dye content ~95% can be used for the detection of acid phosphatase in Clostridium perfringens, and also for the determination of lipase activity. Fast Blue B Salt, Dye content ~95% reacts directly with the active hydroxyl groups in phenolic compounds to determine the content of phenolic substances .

Cat. No.	Product Name	Type

HY-W127711

Fast Blue B Salt, Dye content ~95%	Biochemical Assay Reagents
Fast Blue B Salt, Dye content ~95% is a diazo dye, primarily used as a chromogenic substrate in biochemical analysis. Fast Blue B Salt, Dye content ~95% is the coupling agent for the histochemical demonstration of proteases. Fast Blue B Salt, Dye content ~95% can be used for the detection of acid phosphatase in Clostridium perfringens, and also for the determination of lipase activity. Fast Blue B Salt, Dye content ~95% reacts directly with the active hydroxyl groups in phenolic compounds to determine the content of phenolic substances .

Fast Blue B Salt, Dye content ~95%

Biochemical Assay Reagents

2,6-Dihydroxybenzoic acid	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite
2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

H-Tyr-OMe 1 Publications Verification	Monophenols Classification of Application Fields Other Diseases Phenols Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Tyrosinase
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

H-Tyr-OMe (Standard)	Monophenols Phenols Amino acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Tyrosinase
H-Tyr-OMe is an endogenous metabolite. H-Tyr-OMe quenches the fluorescence of carbon dots by oxidizing the phenolic hydroxyl group to quinone under the catalysis of Tyrosinase, and its amino and thiol binding ability can respond to changes in the concentration of biothiols .

2,6-Dihydroxybenzoic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Phenols Polyphenols Endogenous metabolite Source Classification	Reference Standards Drug Metabolite
2,6-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,6-Dihydroxybenzoic acid (HY-Y0801). This product is used for research and analytical applications. 2,6-Dihydroxybenzoic acid is an aromatic compound containing phenolic hydroxyl groups and carboxyl groups, and it is a secondary metabolite of Salicylic acid (HY-B0167). 2,6-Dihydroxybenzoic acid is also present in olive oil wastewater .

2,5-Dimethylchromone-7-O-β-D-glucopyranoside	Rheum australe D. Don Polygonaceae Plants Saccharides Monosaccharides Source Classification	Others
2,5-Dimethylchromone-7-O-β-D-glucopyranoside is an orally active chromone glycoside found in the underground parts of Rheum australe. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside shows a DPPH radical scavenging activity with an IC₅₀ value of 66.9 μM. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside scavenges free radicals by providing hydrogen atoms through phenolic hydroxyl groups, inhibiting lipid peroxidation. 2,5-Dimethylchromone-7-O-β-D-glucopyranoside is promising for research of oxidative stress-related diseases such as inflammation and skin diseases .

threo-1-(4-Hydroxyphenyl)-1-methoxy-2,3-propanediol	Structural Classification Monophenols Pinaceae Abies delavayi Franch. Phenols Plants Source Classification	Others
threo-1-(4-Hydroxyphenyl)-1-methoxy-2,3-propanediol is an aromatic propanediol phenolic derivative containing methoxy and hydroxyl groups. It can be naturally extracted from the dried aerial parts of Abies delavayi Franch. var. delavayi (Cangshan fir) from Dali, Yunnan, China. This source plant produces anti-inflammatory and anti-tumor active components .

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Phenolic Hydroxyl Groups

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

NaturalProducts

Natural
Products