2. Metabolic Enzyme/Protease
  3. UGT
  4. 3-Methyl-2-nitrophenol

3-Methyl-2-nitrophenol is a UDP-glucuronyltransferase (EC 2.4.1.17) acceptor substrate that can be confirmed to undergo glucuronidation catalyzed by the enzyme to form a glucuronide conjugate. 3-Methyl-2-nitrophenol functions as a substrate for conjugation, with glucuronidation forming a glucuronide conjugate that eliminates the parent compound’s characteristic yellow color. 3-Methyl-2-nitrophenol has higher lipid solubility that contributes to high glucuronidation conversion rate, and exhibits lower absorbance at 340 nm to act as a less interfering substrate for the NADH-NAD+-linked UDP-glucuronyltransferase assay.

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3-Methyl-2-nitrophenol

3-Methyl-2-nitrophenol Chemical Structure

CAS No. : 4920-77-8

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3-Methyl-2-nitrophenol Related Antibodies

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Description

3-Methyl-2-nitrophenol is a UDP-glucuronyltransferase (EC 2.4.1.17) acceptor substrate that can be confirmed to undergo glucuronidation catalyzed by the enzyme to form a glucuronide conjugate. 3-Methyl-2-nitrophenol functions as a substrate for conjugation, with glucuronidation forming a glucuronide conjugate that eliminates the parent compound’s characteristic yellow color. 3-Methyl-2-nitrophenol has higher lipid solubility that contributes to high glucuronidation conversion rate, and exhibits lower absorbance at 340 nm to act as a less interfering substrate for the NADH-NAD+-linked UDP-glucuronyltransferase assay[1].

Molecular Weight

153.14

Formula

C7H7NO3
CAS No.
Appearance

<35°C Solid,>39°C Liquid

SMILES

O=N(=O)C=1C(O)=CC=CC1C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

RT, stored under nitrogen

In solvent -80°C 1 year
-20°C 6 months
Purity & Documentation

Purity: 99.55%

SDS (393 KB)

COA (256 KB) HNMR (111 KB) RP-HPLC (242 KB)

Handling Instructions (2659 KB)
References
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3-Methyl-2-nitrophenol Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-Methyl-2-nitrophenol4920-77-8UGTUDP-glucuronosyltransferaseUridine diphosphate glucuronosyltransferasephenolic hydroxyl groupn-octanolUDP-glucuronyltransferaserat liver microsomesglucuronidationNADH-NAD+-linked assayglucuronide conjugateInhibitorinhibitorinhibit

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