4920-77-8
Chemical Structure
3-Methyl-2-nitrophenol
- CAS. Nr.: 4920-77-8
- Formula:C7H7NO3
- Molecular Weight:153.14
IUPAC Name: 3-methyl-2-nitrophenol
InChIKey: QIORDSKCCHRSSD-UHFFFAOYSA-N
SMILES: O=N(=O)C=1C(O)=CC=CC1C
Biological Activity: 3-Methyl-2-nitrophenol is an acceptor substrate of UDP-glucuronosyltransferase (EC 2.4.1.17) and can undergo glucuronidation catalyzed by this enzyme to form glucuronide conjugates. 3-Methyl-2-nitrophenol enables the glucuronide conjugates formed by its glucuronidation reaction to eliminate the yellow color characteristic of the parent compound[1][2].
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3-Methyl-2-nitrophenol | 3-Methyl-2-nitrophenol is an acceptor substrate of UDP-glucuronosyltransferase (EC 2.4.1.17) and can undergo glucuronidation catalyzed by this enzyme to form glucuronide conjugates. 3-Methyl-2-nitrophenol enables the glucuronide conjugates formed by its glucuronidation reaction to eliminate the yellow color characteristic of the parent compound. | |||||||||||||||||||||
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References
- [1]. Mulder GJ, et al. A rapid NAD+-linked assay for microsomal uridine diphosphate glucuronyltransferase of rat liver and some observations on substrate specificity of the enzyme. Biochem J. 1975;151(1):131-140. [Content Brief]
- [2]. Pan WB, et al. Nitrophenol derivatives oxidized by cerium(IV) ammonium nitrate (CAN) and their cytotoxicity. J Chin Chem Soc. 2005;52:581-8.