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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
Picolyl chloride
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "Picolyl chloride" in MCE Product Catalog:
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Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Biotin-PEG4-Picolyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-D2750
CAS No.: 2669097-38-3
Cat. No.: HY-W007502
CAS No.: 6959-47-3
Synonyms: Picolyl chloride hydrochloride
Cat. No.: HY-140917
CAS No.: 2055048-42-3
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Dde Biotin-PEG4-Picolyl azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Dde Biotin-PEG4-Picolyl azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-W800697
CAS No.: 2644752-87-2
Cat. No.: HY-D3348
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Rhodamine picolyl azide is a fluorescent dye that enables visualization of protein labeling via click chemistry. The detection mechanism of Rhodamine picolyl azide is based on bioorthogonal click chemistry: Rhodamine picolyl azide reacts with the alkyne group on affinity-based protein profiling probes (ABPs) attached to labeled target proteins; this conjugation allows subsequent fluorescence imaging of proteins separated by SDS-PAGE .
Cat. No.: HY-W800696
CAS No.: 2644752-86-1
Cat. No.: HY-D3581
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AF594 Picolyl Azide is a composite fluorescent probe formed by covalent linkage of the Alexa Fluor 594 fluorophore and the Picolyl Azide functional group via chemical bonds. AF594 Picolyl Azide contains a copper chelation domain, and through the copper-catalyzed azide-alkyne cycloaddition click chemistry reaction, it can covalently label alkyne-bearing target molecules and generate fluorescent detection signals. AF594 Picolyl Azide can be used for the detection of alkyne-modified sialylated glycoconjugates, and can also label nascent bacterial polypeptides to determine bacterial protein synthesis rates .
Cat. No.: HY-D3574
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AF488 Picolyl Azide is a Fluorescent dye designed for bioorthogonal visualization applications. AF488 Picolyl Azide functions via copper (I)-catalyzed azide-alkyne cycloaddition click chemistry, where its azide group undergoes covalent reaction with alkyne-functionalized molecules to form fluorescent triazole conjugates. AF488 Picolyl Azide enables the visualization of metabolically labeled isoprenoids in bacteria, which localize to the cell membrane and division septum .
Cat. No.: HY-W756144
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Sulfo-cy3 picolyl azide is a fluorescent dye used for detecting interactions between labeled molecules and proteins based on click chemistry. Sulfo-cy3 picolyl azide undergoes copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) to covalently bind to alkyne-labeled targets, enabling fluorescent detection via scanning. The excitation/emission wavelengths of Sulfo-cy3 picolyl azide are Ex/Em = 550/560 nm. Sulfo-cy3 picolyl azide can be used for in-gel detection of protein-small molecule interactions, as well as labeling ribosome-associated cellular protein targets .
Cat. No.: HY-D3337
Cat. No.: HY-D3577
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AF555 Picolyl Azide is a Fluorescent dye that enables site-specific fluorescent labeling via click chemistry. AF555 Picolyl Azide conjugates with the non-canonical amino acid N-propargyl-L-lysine introduced through ochre stop codon suppression via the copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction, achieving labeling of hyperpolarization-activated cyclic nucleotide-gated HCN channels; its picolyl group accelerates the CuAAC reaction rate, thus completing labeling rapidly at room temperature and minimizing copper-induced cytotoxicity. AF555 Picolyl Azide forms covalent bonds with the alkynyl groups of nucleotide analogs through its azide moiety, labeling viral genomes containing 5-ethynyl-2'-deoxyuridine for visualization via fluorescence microscopy .
Cat. No.: HY-W998839
CAS No.: 2765331-46-0
tris(N-(3-picolyl))phosphoramide is a metal-organic framework (MOF).
Cat. No.: HY-D3584
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AF647 Picolyl Azide is a far-red fluorescent probe used in bioorthogonal click chemistry. It reacts with terminal alkynes via copper-catalyzed azide-alkyne cycloaddition (CuAAC). The integrated picolyl group chelates copper, which speeds up the reaction and allows for lower copper concentrations to protect sensitive proteins (Ex/Em = 650/665 nm)[1].
Cat. No.: HY-D3349
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Fluorne rhodamine picolyl azide is a fluorescent dye used for optical microscopy and nanoscopy, which can be applied in fluorescence correlation spectroscopy (FCS), stimulated emission depletion (STED) nanoscopy, biomolecule labeling, and live-cell imaging .
Cat. No.: HY-W800693
CAS No.: 2841143-99-3
Cat. No.: HY-W800691
CAS No.: 2644752-83-8
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BP Fluor 350 Picolyl Azide is a blue-fluorescent azide-activated probe that reacts with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free click chemistry reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
