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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
Prolyl Hydroxylase inhibitor 1
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "Prolyl Hydroxylase inhibitor 1" in MCE Product Catalog:
Cat. No.: HY-112441
CAS No.: 2205125-60-4
Target:
Research Areas:
Prolyl Hydroxylase inhibitor 1 (Compound 15i) is an orally active hypoxia inducible factor (HIF)-prolyl hydroxylase (PHD) inhibitor with an IC50 of 62.23 nM . Antianemia agent .
9
9 Cited Publications
Synonyms: PG-1016548; AKB-6548
Target:
Research Areas:
Vadadustat (PG-1016548) is a titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor . Vadadustat is an erythropoiesis-stimulating agent and has the potential for anemia treatment in chronic kidney disease in vivo .
2
2 Cited Publications
Target:
Research Areas:
M1002 is a hypoxia-inducible factor-2 (HIF-2) agonist, and can enhance the expression of HIF-2 target genes. M1002 shows synergy with prolyl-hydroxylase domain (PHD) inhibitors .
Target:
Research Areas:
BNS is a cell penetrant, potent and selective PHD2 (prolyl-hydroxylase 2) inhibitor .
Cat. No.: HY-403658
CAS No.: 931400-77-0
Research Areas:
IOX2-NH2 (example 115) is a derivative of IOX2 (HY-15468). IOX2 is a chemical probe, and a specific prolyl hydroxylase-2 (PHD2) inhibitor .
Cat. No.: HY-101277S1
Synonyms: PG-1016548-13C6; AKB-6548-13C6
Cat. No.: HY-101277R
CAS No.: 1000025-07-9
Synonyms: PG-1016548 (Standard); AKB-6548 (Standard)
Research Areas:
Vadadustat (Standard) is the analytical standard of Vadadustat (HY-101277). This product is intended for research and analytical applications. Vadadustat (PG-1016548) is a titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor . Vadadustat is an erythropoiesis-stimulating agent and has the potential for anemia treatment in chronic kidney disease in vivo .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
