2 Results for "

Prostaglandin E2 (GMP)

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Prostaglandin E2 (GMP)" in MCE Product Catalog:

Prostaglandin E2 (GMP)
Prostaglandin E2 (GMP)
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Cat. No.: HY-101952G
CAS No.: 363-24-6
Purity:  99.0%
Synonyms: PGE2 (GMP); Dinoprostone (GMP)
Prostaglandin E2 (GMP) is Prostaglandin E2 (HY-101952) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Prostaglandin E2, an inflammatory mediator, is a endogenous hormone-like substance that participate in a wide range of body functions .
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IM-12 (GMP)
IM-12 (GMP)
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Cat. No.: HY-12292G
CAS No.: 1129669-05-1
IM-12 GMP is IM-12 (HY-12292) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IM-12 is an orally active anti-inflammatory agent that targets and inhibits the NF-κB and STAT3 signaling pathways. IM-12 activates the Wnt signaling pathway and promotes the nuclear translocation of β-catenin by inhibiting GSK3β, while also blocking the tyrosine kinase activity of p210BCR/ABL. IM-12 reduces the levels of IL-6, IL-17, NO, prostaglandin E2, iNOS and COX-2, and induces ER stress, Ca 2+ release, autophagy and apoptosis. IM-12 is heat-sensitive and does not induce autophagy in IM-resistant p210BCR/ABL T315I mutant cells. IM-12 is also a component of the 5iLA medium used for naive pluripotent stem cell research. IM-12 has been applied in studies related to carrageenan (HY-125474)-induced hind paw edema, TNBS-induced colitis, and acute and chronic myeloid leukemia .
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