2 Results for "

Protease (Fab Cleaving)

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Protease (Fab Cleaving)" in MCE Product Catalog:

Cat. No.: HY-E70566
Target:  

Ser/Thr Protease

Research Areas:  

Others

Protease (Fab Cleaving) is a serine protease expressed recombinantly in E.coli with a 6×His tag at the C-terminus. Protease (Fab Cleaving) specifically digests human IgG1 at a single site above the hinge, generating intact Fab and Fc fragments within two hours without reducing conditions.
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1
1 Cited Publications
Cat. No.: HY-E70365A
Research Areas:  

Inflammation/Immunology

IdeS (Immobilized, Microspin) is a resin that covalently couples IdeS protease to agarose beads and cleaves IgG at specific sites to generate F(ab')2 and Fc fragments. After IdeS (Immobilized, Microspin) digestion, F(ab')2 and Fc fragments are obtained in the solution without IdeS enzyme.
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