11 Results for "

Pyrroline-5-carboxylate

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "Pyrroline-5-carboxylate" in MCE Product Catalog:

Cat. No.: HY-138354
CAS No.: 2139-03-9
Target:  

Drug Intermediate

Research Areas:  

Infection

Pyrroline-5-carboxylate is a key intermediate in proline anabolism and catabolism. Pyrroline-5-carboxylate plays important roles in plant defense against pathogen invasion, as well as in redox regulation, nucleotide synthesis and other processes in animal cells .
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2
2 Cited Publications
Cat. No.: HY-126271
CAS No.: 709-85-3
Purity:  99.79%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

PYCR1-IN-1 (compound 4) is a pyrroline-5-carboxylate reductase 1 (PYCR1) inhibitor with an IC50 of 8.8 µM. PYCR1-IN-1 has anticancer effects .
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1
1 Cited Publications
Cat. No.: HY-P76138
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ALDH4A1; Mitochondrial Delta-1-Pyrroline 5-carboxylate Dehydrogenase; Prev. ALDH4; Aldehyde Dehydrogenase 4 Family, Member A1; L-Glutamate Gamma-Semialdehyde Dehydrogenase; Epididymis Secretory Sperm Binding Protein; P5CDh; Multifunctional Fusion Protein
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-138354A
CAS No.: 72978-16-6
Purity:  98.87%
Target:  

Drug Intermediate

Research Areas:  

Infection

Pyrroline-5-carboxylate sodium is a key intermediate in proline anabolism and catabolism. Pyrroline-5-carboxylate sodium plays important roles in plant defense against pathogen invasion, as well as in redox regulation, nucleotide synthesis and other processes in animal cells .
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Cat. No.: HY-114118S
Semaglutide-d8 is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer [5].
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Cat. No.: HY-114118S1
Semaglutide-d8 tetraTFA is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer [5].
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Cat. No.: HY-P703182
Synonyms: PYCR1; ARCL2B; Pyrroline-5-carboxylate Reductase 1; ARCL3B; P5C; P5CR 1; Pyrroline-5-carboxylate Reductase 1, Mitochondrial; PIG45; P5C Reductase 1; PP222; Truncated Pyrroline-5-carboxylate Reductase 1; P5CR; Proliferation-Inducing Protein 45; PRO3; Pyrro
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P86769
Synonyms: AL4A1_HUMAN antibody; aldehyde dehydrogenase 4 antibody; aldehyde dehydrogenase 4 family, member A1 antibody; Aldehyde dehydrogenase family 4 member A1 antibody; Aldehyde dehydrogenase, family 4, subfamily A, member 1 antibody; ALDH4 antibody; aldh4a1 antibody; Delta 1 Pyrroline 5 carboxylate dehydrogenase, mitochondrial antibody; Delta-1-Pyrroline-5-carboxylate dehydrogenase antibody; L-glutamate gamma-semialdehyde dehydrogenase antibody; AL4A1_HUMAN antibody; aldehyde dehydrogenase 4 antibody; aldehyde dehydrogenase 4 family, member A1 antibody; Aldehyde dehydrogenase family 4 member A1 antibody; Aldehyde dehydrogenase, family 4, subfamily A, member 1 antibody; ALDH4 antibody; aldh4a1 antibody; Delta 1 Pyrroline 5 carboxylate dehydrogenase, mitochondrial antibody; Delta-1-Pyrroline-5-carboxylate dehydrogenase antibody; L-glutamate gamma-semialdehyde dehydrogenase antibody; mitochondrial antibody; mitochondrial delta-1-Pyrroline 5-carboxylate dehydrogenase antibody; P5C dehydrogenase antibody; P5CD antibody; P5CDh antibody; P5CDhL antibody; P5CDhS antibody; Pyrroline-5-carboxylate dehydrogenase antibody; RP11 128M10.1 antibody;

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, IF-Tissue

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P704179
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ALDH18A1; Spastic Paraplegia 9 (Autosomal Dominant); Prev. GSAS; Delta-1-Pyrroline-5-carboxylate Synthetase; Prev. PYCS; Delta1-Pyrroline-5-Carboxlate Synthetase; Prev. SPG9; ARCL3A; P5CS; ADCL3; Delta-1-Pyrroline-5-carboxylate Synthase; SPG9A; Pyrroline-
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P811163
Synonyms: GSAS, P5CS, PYCS, ALDH18A1, Delta-1-Pyrroline-5-carboxylate synthase, Aldehyde dehydrogenase family 18 member A1

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse

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Cat. No.: HY-P76139
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ALDH4A1; Mitochondrial Delta-1-Pyrroline 5-carboxylate Dehydrogenase; Prev. ALDH4; Aldehyde Dehydrogenase 4 Family, Member A1; L-Glutamate Gamma-Semialdehyde Dehydrogenase; Epididymis Secretory Sperm Binding Protein; P5CDh; Multifunctional Fusion Protein
Species:  
Human
Source:  
Sf9 insect cells
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