3 Results for "

RND-type efflux pumps

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "RND-type efflux pumps" in MCE Product Catalog:

Hydroquinine
Hydroquinine
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Cat. No.: HY-42034
CAS No.: 522-66-7
Synonyms: Dihydroquinine
Category:  

Alkaloids Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants Disease Research Fields Inflammation/Immunology

Target:  

Bacterial Parasite Reactive Oxygen Species (ROS) Protein Arginine Deiminase

Hydroquinine (Dihydroquinine) is an anti-bacterial agent that inhibits both Gram-positive and Gram-negative bacteria. Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes. Hydroquinine inhibits Plasmodium falciparum and Plasmodium berghei. Hydroquinine displays anti-malarial and demelanizing activities. Hydroquinine effectively induces specific RND-type efflux pump systems in Pseudomonas aeruginosa, particularly the MexCD-OprJ and MexXY efflux pumps. Hydroquinine inhibits Pseudomonas aeruginosa adhesion and biofilm formation. Hydroquinine serves as a precursor for derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine, and 10,11-dihydroquinine monohydrochloride .
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Hydroquinine (Standard)
Hydroquinine (Standard)
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Cat. No.: HY-42034R
CAS No.: 522-66-7
Synonyms: Dihydroquinine (Standard)
Category:  

Alkaloids Rubiaceae Cinchona calisaya Wedd. Quinoline Alkaloids Plants

Target:  

Reference Standards Bacterial Parasite Reactive Oxygen Species (ROS) Protein Arginine Deiminase

Hydroquinine (Standard) is the analytical standard of Hydroquinine. Hydroquinine (Dihydroquinine) is an anti-bacterial agent that inhibits both Gram-positive and Gram-negative bacteria. Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes. Hydroquinine inhibits Plasmodium falciparum and Plasmodium berghei. Hydroquinine displays anti-malarial and demelanizing activities. Hydroquinine effectively induces specific RND-type efflux pump systems in Pseudomonas aeruginosa, particularly the MexCD-OprJ and MexXY efflux pumps. Hydroquinine inhibits Pseudomonas aeruginosa adhesion and biofilm formation. Hydroquinine serves as a precursor for derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine, and 10,11-dihydroquinine monohydrochloride .
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MBX2319
MBX2319
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Cat. No.: HY-188076
CAS No.: 375836-83-2
Target:  

Bacterial

Research Areas:  

Infection

MBX2319 is an AcrB inhibitor and antibiotic efficacy restorer that potently inhibits RND-type efflux pumps of Enterobacteriaceae species. MBX2319 increases antibacterial activity of fluoroquinolone and β-lactam antibiotics against Escherichia coli, restores antibiotic efficacy, and reduces antibiotic MIC against Gram-negative bacteria. MBX2319 has no inherent antibacterial activity against Escherichia coli and does not alter bacterial outer membrane permeability. MBX2319 can be used for the research of gram-negative bacterial infections and multidrug-resistant gram-negative bacterial infections .
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