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Pathways Recommended:	Stem Cell/Wnt Cell Cycle/DNA Damage

Results for "

SGC-7901 Cells

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Apoptosis (12) Atg8/LC3 (1) Autophagy (1) Bacterial (1) Bcl-2 Family (1) c-Met/HGFR (1) Caspase (1) CDK (1) DNA/RNA Synthesis (1) Drug Derivative (1) EGFR (1) Endogenous Metabolite (2) Environmental Pollutants (2) Isotope-Labeled Compounds (1) JAK (1) Liposome (1) Microtubule/Tubulin (5) mTOR (1) NF-κB (1) p38 MAPK (1) PAK (1) PARP (1) Phosphatase (1) Reactive Oxygen Species (ROS) (1) Reference Standards (2) STAT (2) Survivin (1) YAP (1)
By Research Areas:	Cancer (26) Infection (2) Inflammation/Immunology (1)

By Targets:

Akt (2)

Apoptosis (12)

Atg8/LC3 (1)

Autophagy (1)

Bacterial (1)

Bcl-2 Family (1)

c-Met/HGFR (1)

Caspase (1)

CDK (1)

DNA/RNA Synthesis (1)

Drug Derivative (1)

EGFR (1)

Endogenous Metabolite (2)

Environmental Pollutants (2)

Isotope-Labeled Compounds (1)

JAK (1)

Liposome (1)

Microtubule/Tubulin (5)

mTOR (1)

NF-κB (1)

p38 MAPK (1)

PAK (1)

PARP (1)

Phosphatase (1)

Reactive Oxygen Species (ROS) (1)

Reference Standards (2)

STAT (2)

Survivin (1)

YAP (1)

By Research Areas:

Cancer (26)

Infection (2)

Inflammation/Immunology (1)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Nuclear Factor of activated T Cells (NFAT) TREM receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W015084

β-Ionone 1 Publications Verification	Environmental Pollutants Apoptosis	Cancer
β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .

HY-W015084A

(E)-β-Ionone β-Lonone	Environmental Pollutants Apoptosis	Cancer
(E)-β-Ionone is the isomer of β-Ionone (HY-W015084). β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. β-Ionone has anti-cancer activity .

HY-N4148

Purpureaside C	DNA/RNA Synthesis Apoptosis Bacterial	Infection Inflammation/Immunology Cancer
Purpureaside C, phenolic glycoside, is a minichromosome maintenance complex component 6 (MCM6) inhibitor. Purpureaside C binds to the ATP-pocket of MCM6, suppresses MCM6 protein expression in gastric cancer cells. Purpureaside C suppresses gastric cancer cell growth and induces apoptosis. Purpureaside C exerts antibacterial activity and proinflammatory activity. Purpureaside C can be used for the researches of gastric cancer, bacterial infection and inflammation .

HY-155360

MY-1076 1 Publications Verification	YAP Apoptosis	Cancer
MY-1076 is an inhibitor of YAP. MY-1076 induces YAP degradation and cell apoptosis. MY-1076 inhibits MGC-803, SGC-7901, HCT-116 and KYSE450 cells proliferation with IC₅₀ s of 0.019, 0.017, 0.020 and 0.044 μM, respectively .

HY-W001084

Methyl 4-hydroxyphenylacetate	Others	Infection Cancer
Methyl 4-hydroxyphenylacetate is a compound found in the marine fungus Penicillium oxalicum 0312F1. Methyl 4-hydroxyphenylacetate can be Methyl 4-hydroxyphenylacetate inhibits replication of tobacco mosaic virus (TMV) in Nicotiana tabacum leaf discs. Methyl 4-hydroxyphenylacetate shows inhibitory activity against proliferation of cancer cells. Methyl 4-hydroxyphenylacetate can be used for the researches of TMV infection and cancer .

HY-N6651

Isocryptotanshinone	STAT Phosphatase Apoptosis Autophagy p38 MAPK EGFR JAK Bcl-2 Family Survivin Akt mTOR PARP Caspase Atg8/LC3 CDK	Cancer
Isocryptotanshinone is a dual STAT3 and PTP1B (IC₅₀ = 56.1 μM) inhibitor. Isocryptotanshinone inhibits STAT3 by binding to the STAT3 SH2 domain to block phosphorylation and nuclear translocation ^[1][2]. Isocryptotanshinone exerts its anti-proliferative effect via the induction of cell cycle arrest, apoptosis, and pro-death autophagy, through the regulation of STAT3, AKT/mTOR and MAPK signaling pathways. Isocryptotanshinone suppresses the xenograft gastric cancer (GC) tumor growth in BALB/c nude mice. Isocryptotanshinone can be used for cancer research, such as lung cancer, breast cancer and GC .

HY-N7980

Rubipodanone A	NF-κB	Cancer
Rubipodanone A, a naphthohydroquinone dimer, shows cytotoxicity against A549, BEL-7402, HeLa, HepG2, SGC-7901 and U251 cells. Rubipodanone A also shows obvious activating effect at 20 and 40 μM for NF-κB .

HY-N10201

Cytoglobosin C	Endogenous Metabolite	Cancer
Cytoglobosin C, a cytochalasan derivative, shows potent cytotoxicity against both SGC-7901 and A549 cell lines (IC₅₀<10 μM) .

HY-124398

GL-1196	PAK	Cancer
GL-1196 is an inhibitor of PAK4. GL-1196 can suppress the proliferation and invasion of gastric cancer cells. GL-1196 inhibits PAK4-mediated signaling pathways. GL-1196 can hinder the proliferation of human gastric cancer cells through suppressing PAK4/c-Src/EGFR/CyclinD1 and CDK4/6. GL-1196 can reduce filamentous pseudopodia formation and induce filamentous pseudopodia formation and promote cell elongation in SGC7901 and BGC823 cells. GL-1196 can be studied in anti-cancer research .

HY-161351

STAT3/AKT-IN-1	Akt STAT Apoptosis	Cancer
STAT3/AKT-IN-1 is a dual inhibitor for the signal transducer and activator of transcription 3 (STAT3) and protein kinase B (AKT) signalling pathway, exhibits antitumor activity against gastric cancer and induces cell apoptosis in SGC-7901 cells .

HY-N1841

Rocaglamide D 3'-Hydroxyrocaglamide	Others	Cancer
Rocaglamide D (3'-Hydroxyrocaglamide) (compound 1) is a lignan that can be found in Aglaia odorata. Rocaglamide D shows cytotoxicity with IC₅₀s of 0.32, 0.12, 0.25 µM for HeLa, SGC-7901, A549 cells, respectively .

HY-156098

c-Met-IN-19	c-Met/HGFR	Cancer
c-Met-IN-19 (Compound 21j) is a c-Met inhibitor (IC₅₀: 1.99 nM). c-Met-IN-19 shows cytotoxicity against A549, HT-29, SGC-7901, MDA-MB-231 cells with IC₅₀s of 0.25, 0.36, 0.98, 0.76 μM .

HY-146311

Tubulin polymerization-IN-16	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-16 (compound 5g) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-16 shows most potent against cancer cells, with IC₅₀ values of 0.084-0.221 μM. Tubulin polymerization-IN-16 potently disrupts microtubule/tubulin dynamics, induces cell cycle arrest at G2/M phase in SGC-7901 cells .

HY-W015084S

β-Ionone-13C3	Isotope-Labeled Compounds Apoptosis	Cancer
β-Ionone- ¹³C₃ is the ¹³C-labeled β-Ionone. β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .

HY-W015084R

β-Ionone (Standard)	Reference Standards Apoptosis	Cancer
β-Ionone (Standard) is the analytical standard of β-Ionone. This product is intended for research and analytical applications. β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity .

HY-176162

BJ-13	Reactive Oxygen Species (ROS) Apoptosis	Cancer
BJ-13 is a reactive oxygen species (ROS) inducer that can lead to mitochondrial membrane potential collapse and caspase-dependent apoptosis. BJ-13 inhibits the proliferation of SGC-7901, U-87MG, and HepG-2 cancer cells (IC₅₀ values of 15.33, 27.18, and 20.44 nM, respectively). BJ-13 can be used in the study of gastric cancer .

HY-N13136

Timosaponin D	Others	Cancer
Timosaponin D, a natural steroid saponin, can be obtained from the rhizome of Anemarrhena asphodeloides. The IC₅₀ values of Timosaponin D against HepG2 and SGC7901 cells are 43.90 and 57.90 μM, respectively. Timosaponin D can be used in anticancer research .

HY-147947

Tubulin polymerization-IN-30	Microtubule/Tubulin	Cancer
Tubulin polymerization-IN-30 (compound 6e) is a potent Tubulin polymerization inhibitor. Tubulin polymerization-IN-30 is a colchicine binding site inhibitor. Tubulin polymerization-IN-30 can disrupt intracellular microtubule organization, arrest cell cycle at the G2/M phase. Tubulin polymerization-IN-30 exhibits the high potency against the cancer cell lines including SGC-7901, A549 and HeLa, with IC₅₀ values of 2.16, 2.21, and 0.403 μM .

HY-168102

Antiproliferative agent-59	Microtubule/Tubulin Apoptosis	Cancer
Antiproliferative agent-59 (Compound 14u) is an inhibitor for tubulin polymerization. Antiproliferative agent-59 exhibits antiproliferative activities against cancer cells Huh7, SGC-7901, and MCF-7 with IC₅₀ of 0.03, 0.18, and 0.13μM. Antiproliferative agent-59 arrests the cell cycle at G2/M phase and induces apoptosis in Huh7 cell. Antiproliferative agent-59 exhibits antitumor efficacy against liver cancer in Huh7 xenograft mouse models, without significant toxicity .

HY-W015084AR

(E)-β-Ionone (Standard) β-Lonone (Standard)	Apoptosis Reference Standards	Cancer
(E)-β-Ionone (Standard) is the analytical standard of (E)-β-Ionone. This product is intended for research and analytical applications. (E)-β-Ionone is the isomer of β-Ionone (HY-W015084). β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. β-Ionone has anti-cancer activity .

HY-117473

DAT-230	Microtubule/Tubulin Apoptosis	Cancer
DAT-230 is a microtubule inhibitor. DAT-230 induces cell apoptosis and results in microtubule de-polymerization and G2/M phase arrest. DAT-230 inhibits cell growth in vitro and in vivo .

HY-155686

Tubulin polymerization-IN-44	Microtubule/Tubulin	Cancer
Tubulinpolymer-in-44 (compound 7w) is a strong and effective Tubulin inhibitor, with an IC₅₀ value of 0.21 μM. Tubulinpolymer-in-44 induces apoptosis by arresting G2/M phase, which can be used for cancer research.

HY-N17005

3-O-(p-Hydroxybenzoyl)serratriol	Others	Cancer
3-O-(p-Hydroxybenzoyl)serratriol is a serratene-type triterpenoid compound with low cytotoxicity against cancer cells (IC₅₀ >100 μg/mL against three human cancer cell lines: K562, SMMC-7721, and SGC7901). 3-O-(p-Hydroxybenzoyl)serratriol can be naturally extracted from the whole plant of Palhinhaea cernua .

HY-N17349

(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol	Endogenous Metabolite	Cancer
(23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol (compound 3) is a cytotoxin that can be found in the marine bryozoan Bugula neritina. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol shows weak cytotoxicity against SGC7901 cell with an IC₅₀ value of 111.8 μM. (23S,24R)-Dimethylcholest-7-ene-3b,5a,6b-triol can be used for the research of hepatocellular carcinoma, gastric carcinoma .

HY-N17608

10(14)-Guaien11-ol	Others	Others
10 (14)-Guaien-11-ol is a guaiane-type sesquiterpenoid that exists in the roots of Jatropha curcas. 10 (14)-Guaien-11-ol shows no significant growth inhibitory activity against human gastric cancer cells .

HY-N18292

Qinanone G	Drug Derivative	Cancer
Qinanone G is a 2-(2-phenylethyl)chromone (HY-N8220) derivative found in the high quality Chinese agarwood 'Qi-Nan' from Aquilaria sinensis (Lour.) Glig. Qinanone G shows no inhibitory activity against AChE and cancer cells .

HY-N18174

Glaucogenin E	Others	Others
Glaucogenin E is a C₂₁ steroid sapogenin found in rhizomes of Cynanchum stauntonii (Decne.) Schltr. ex Levl. Glaucogenin E shows no cytotoxic activity against human cancer cells .

HY-182988

L-Arg-DSPE	Liposome	Cancer
L-Arg-DSPE is an arginine-functionalized DSPE lipid containing free guanidine groups. L-Arg-DSPE serves as a component of NO-responsive degradable drug-loaded liposomal nanomotors (L-Arg@Lip-DOX), promoting drug deep tumor tissue penetration and cellular internalization. L-Arg-DSPE can be used for the research of drug delivery .

Cat. No.	Product Name	Category	Target	Chemical Structure