3098360-50-7
3098360-50-7
Chemical Structure
c-Met-IN-19
- CAS No.: 3098360-50-7
- Formula:C34H37Cl2FN4O7S
- Molecular Weight:735.65
InChIKey: WFZSEUZHWATVDN-UHFFFAOYSA-N
SMILES: COC1=CC2=C(N=CC=C2OC3=CC=C(NC(CCOC)=NS(=O)(CC4=C(Cl)C=CC=C4Cl)=O)C=C3F)C=C1OCCCN5CCOCC5
Biological Activity: c-Met-IN-19 (Compound 21j) is a c-Met inhibitor (IC50: 1.99 nM). c-Met-IN-19 shows cytotoxicity against A549, HT-29, SGC-7901, MDA-MB-231 cells with IC50s of 0.25, 0.36, 0.98, 0.76 μM[1].
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c-Met-IN-19 | c-Met-IN-19 (Compound 21j) is a c-Met inhibitor (IC50: 1.99 nM). c-Met-IN-19 shows cytotoxicity against A549, HT-29, SGC-7901, MDA-MB-231 cells with IC50s of 0.25, 0.36, 0.98, 0.76 μM. | |||||||||||||||||||||
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References
Keywords
