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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
Sestrin2-GATOR2
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "Sestrin2-GATOR2" in MCE Product Catalog:
Cat. No.: HY-W074912
CAS No.: 122565-28-0
Synonyms: (S)-5,5,5-Trifluoronorvaline; H-Nva(5,5,5-triF)-OH
Target:
Research Areas:
(S)-2-Amino-5,5,5-trifluoropentanoic acid ((S)-5,5,5-Trifluoronorvaline; H-Nva (5,5,5-triF)-OH) is a selective Sestrin-GATOR2 modulator that indirectly inhibits mTORC1 activity via a competitive binding mechanism. (S)-2-Amino-5,5,5-trifluoropentanoic acid can be used in research on cancer, metabolic diseases, neurodegenerative diseases, and muscle atrophy .\n
Cat. No.: HY-W073239
CAS No.: 122565-29-1
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
(R)-2-Amino-5,5,5-trifluoropentanoic acid is a leucine antagonist. (R)-2-Amino-5,5,5-trifluoropentanoic acid increases Sestrin2 binding to GATOR2. (R)-2-Amino-5,5,5-trifluoropentanoic acid can be used in research on diabetes, neurodegenerative diseases, immune diseases, and cancer .
Cat. No.: HY-W078733
CAS No.: 15960-05-1
Synonyms: (2S)-2-Amino-4,4,4-trifluorobutanoic acid
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
(S)-2-Amino-4,4,4-trifluorobutanoic acid ((2S)-2-Amino-4,4,4-trifluorobutanoic acid) is a Sestrin-GATOR2 modulator. (S)-2-Amino-4,4,4-trifluorobutanoic acid can be used in research on diabetes, neurodegenerative diseases, immune diseases, and cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
