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Sorbitol

" in MedChemExpress (MCE) Product Catalog:

47

Inhibitors & Agonists

4

Fluorescent Dye

8

Biochemical Assay Reagents

5

Natural
Products

1

Recombinant Proteins

13

Isotope-Labeled Compounds

2

Antibodies

1

Oligonucleotides

4

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0400
    D-Sorbitol
    2 Publications Verification

    Sorbitol; D-Glucitol

    Environmental Pollutants Endogenous Metabolite Bacterial Others
    D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement .
    D-Sorbitol
  • HY-B0342

    Methylglucamine; Meglumin; Methylglucamin

    Biochemical Assay Reagents Cancer
    Meglumine (Methylglucamine) is an orally active amino sugar derived from sorbitol. Meglumine has anti-inflammatory and antitumor activity. Meglumine is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide .
    Meglumine
  • HY-106697
    Ponalrestat
    1 Publications Verification

    ICI 128436

    Aldose Reductase Metabolic Disease
    Ponalrestat (ICI 128436) is an orally active, selective and noncompetitive aldose reductase (AKR1B1; ALR) inhibitor. Ponalrestat selectively inhibits ALR2 (Ki=7.7 nM) over ALR1 (Ki=60 μM). Ponalrestat inhibits the conversion of glucose to sorbitol .
    Ponalrestat
  • HY-118980

    Aldehyde Dehydrogenase (ALDH) Metabolic Disease
    Sorbitol dehydrogenase-IN-1 is a potent and orally active sorbitol dehydrogenase inhibitor with IC50 s of 4, 5 nM for rat and human, respectively. Sorbitol Dehydrogenase (SDH) is an enzyme that belongs to the zinc-containing alcohol dehydrogenase (ADH) family. ADH and ALDH are enzymes that work together to metabolize alcohol .
    Sorbitol dehydrogenase-IN-1
  • HY-15314
    Ranirestat
    1 Publications Verification

    AS-3201

    Aldose Reductase Neurological Disease Metabolic Disease
    Ranirestat (AS-3201) potent and orally active aldose reductase (AR) inhibitor with IC50s of 11 nM and 15 nM for rat lens AR and recombinant human AR, respectively, and a Ki of 0.38 nM for recombinant human AR. Ranirestat has the potential for diabetic sensorimotor polyneuropathy treatment. Ranirestat also has a neuroprotective effect on diabetic retinas .
    Ranirestat
  • HY-B0400B

    Sorbito, for cell culture; D-Glucitol, for cell culture

    Environmental Pollutants Biochemical Assay Reagents Others
    D-Sorbitol (D-Glucitol), for cell culture is a six-carbon sugar alcohol that can be used as a sugar substitute. D-Sorbitol, for cell culture serves as an osmotic regulator, cryoprotectant and carbon source in various plant and microbial cell culture media .
    D-Sorbitol, for cell culture
  • HY-B0400S1

    Sorbitol-13C; D-Glucitol-13C

    Endogenous Metabolite Others
    D-Sorbitol- 13C is the 13C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary s
    D-Sorbitol-13C
  • HY-50289
    Sorbinil
    2 Publications Verification

    Aldose Reductase Metabolic Disease
    Sorbinil is an aldose reductase inhibitor (ARI) that prevents the accumulation of sorbitol in cells or animals. Sorbinil is useful in studying diabetes and diabetic complications, reducing AR activity and inhibiting the polyol pathway.
    Sorbinil
  • HY-E70398

    L-Iditol dehydrogenase; Polyol dehydrogenase; SDH

    Biochemical Assay Reagents Metabolic Disease
    Sorbitol dehydrogenase (L-Iditol dehydrogenase) is an oxidoreductasea and catalyses the conversion of sorbitol to fructose with NAD + as the coenzyme. Sorbitol dehydrogenase catalyses pH-dependent redox reactions between NAD +/NADH and sorbitol/fructose. Sorbitol dehydrogenase is implicated in diabetic complications and is a biomarker of drug-induced liver injury. Sorbitol dehydrogenase can be used for the research of diabetes and liver injury .
    Sorbitol dehydrogenase
  • HY-W115716

    Span 85

    Environmental Pollutants Biochemical Assay Reagents Others
    Sorbitan trioleate (Span 85) is an orally active non-ionic surface active agent. Sorbitan trioleate can be used as an excipient, such as surfactant, emulsifier, lubricant, wetting agent, dispersant, thickener, defoamer .
    Sorbitan trioleate
  • HY-B0400S16

    Sorbitol-13C6; D-Glucitol-13C6

    Bacterial Endogenous Metabolite Others
    D-Sorbitol- 13C6 is the 13C labeled D-Sorbitol . D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement .
    D-Sorbitol-13C6
  • HY-164605

    Aldehyde Dehydrogenase (ALDH) Metabolic Disease
    (6S)-CP-470711 (Compound 8) is an inhibitor for sorbitol dehydrogenase, that inhibits human and rat SDH with IC50 of 19 nM and 27 nM. (6S)-CP-470711 ameliorates the Streptozotocin (HY-13753)-induced diabetes in rats models .
    (6S)-CP-470711
  • HY-B0400R

    Sorbitol (Standard); D-Glucitol (Standard)

    Reference Standards Endogenous Metabolite Bacterial Others
    D-Sorbitol (Standard) is the analytical standard of D-Sorbitol. This product is intended for research and analytical applications. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement .
    D-Sorbitol (Standard)
  • HY-B0400S

    Sorbitol-d8; D-Glucitol-d8

    Endogenous Metabolite Others
    D-Sorbitol-d8 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement .
    D-Sorbitol-d8
  • HY-W763560

    Biochemical Assay Reagents Others
    Sorbitan Sesquioleate is a synthetic surfactant and emulsifier based on sorbitol and modified oleic acid .
    Sorbitan Sesquioleate
  • HY-106915

    SPR 210

    Aldose Reductase Neurological Disease Metabolic Disease
    SG-210 (SPR 210) is an orally active and selective aldose reductase (AR) inhibitor. SG-210 has IC50 values of 9.5 nM and 10 nM for AR from porcine lens and human placenta, respectively. SG-210 can inhibit sorbitol accumulation and ameliorate diabetic neuropathy and retinopathy in Streptozotocin (HY-13753)-induced diabetic rats. SG-210 can be used in the research of diseases such as diabetes-related complications .
    SG-210
  • HY-113738

    Aldose Reductase Na+/K+ ATPase Endogenous Metabolite Neurological Disease Metabolic Disease
    ADN-138 is an aldose reductase inhibitor. ADN-138 reduces sorbitol levels in diabetic nerves and results in significant increases in MNCV and Na +, K +-ATPase in the nerves. ADN-138 can be used in the research of diabetic nerve complications .
    ADN 138
  • HY-144391

    Fungal Inflammation/Immunology
    Chitin synthase inhibitor 1 is a potent and selective chitin synthase (CHS) inhibitor (IC50=0.12 mM). Chitin synthase inhibitor 1 has potent antifungal activity against drug-resistant fungi variants .
    Chitin synthase inhibitor 1
  • HY-164698

    Aldehyde Dehydrogenase (ALDH) Neurological Disease Metabolic Disease
    CP-470711 is an orally active and potent and selective sorbitol dehydrogenase (SDH) inhibitor with an IC50=10 nM for human SDH and IC50=17 nM for rat SDH. CP-470711 is promising for research of chronic complications related to type 2 diabetes mellitus, such as neuropathy and nephropathy .
    CP-470711
  • HY-B0400S4

    Sorbitol-d2; D-Glucitol-d2

    Isotope-Labeled Compounds Endogenous Metabolite Others
    D-Sorbitol-d2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and diet
    D-Sorbitol-d2
  • HY-B0400S10

    Sorbitol-d4; D-Glucitol-d4

    Endogenous Metabolite Others
    D-Sorbitol-d4 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and diet
    D-Sorbitol-d4
  • HY-B0400AS

    Endogenous Metabolite Bacterial Isotope-Labeled Compounds Others
    L-Sorbitol- 13C is the 13C labeled L-Sorbitol .
    L-Sorbitol-13C
  • HY-B0400S7

    Sorbitol-d1-2; D-Glucitol-d1-2

    Endogenous Metabolite Others
    D-Sorbitol-d-2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di
    D-Sorbitol-d1-2
  • HY-B0400S9

    Sorbitol-d2-2; D-Glucitol-d2-2

    Endogenous Metabolite Others
    D-Sorbitol-d2-2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di
    D-Sorbitol-d2-2
  • HY-B0400S8

    Sorbitol-d2-1; D-Glucitol-d2-1

    Endogenous Metabolite Others
    D-Sorbitol-d2-1 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di
    D-Sorbitol-d2-1
  • HY-B0400S2

    Sorbitol-13C-1; D-Glucitol-13C-1

    Isotope-Labeled Compounds Endogenous Metabolite Others
    D-Sorbitol- 13C-1 is the 13C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary
    D-Sorbitol-13C-1
  • HY-B0400S15

    Sorbitol-18O-1; D-Glucitol-18O-1

    Endogenous Metabolite Others
    D-Sorbitol- 18O-1 is the 18O labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary
    D-Sorbitol-18O-1
  • HY-B0400S3

    Sorbitol-13C-2; D-Glucitol-13C-2

    Isotope-Labeled Compounds Endogenous Metabolite Others
    D-Sorbitol- 13C-2 is the 13C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary
    D-Sorbitol-13C-2
  • HY-B0400CGL

    Sorbitol, M150 (GMP Like); D-Glucitol, M150 (GMP Like)

    Endogenous Metabolite Others
    D-Sorbitol, M150 (GMP Like) is the GMP Like class D-Sorbitol, M150 that can be used as pharmaceutical excipients. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement .
    D-Sorbitol, M150 (GMP Like)
  • HY-B0400EGL

    Endogenous Metabolite Others
    D-Sorbitol, M400 (GMP Like) is the GMP Like class D-Sorbitol, M400 that can be used as pharmaceutical excipients. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement .
    D-Sorbitol, M400 (GMP Like)
  • HY-B0400DGL

    Endogenous Metabolite Others
    D-Sorbitol, M200 (GMP Like) is the GMP Like class D-Sorbitol, M200 that can be used as pharmaceutical excipients. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary supplement .
    D-Sorbitol, M200 (GMP Like)
  • HY-B0400AS1

    Endogenous Metabolite Bacterial Isotope-Labeled Compounds Others
    L-Sorbitol- 13C-1 is the 13C labeled L-Sorbitol .
    L-Sorbitol-13C-1
  • HY-W558950

    Biochemical Assay Reagents
    D-Sorbitol hexaacetate is a kind of biochemical reagent.
    D-Sorbitol hexaacetate
  • HY-B0400A

    L-Glucitol

    Biochemical Assay Reagents Others
    L-Sorbitol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    L-Sorbitol
  • HY-E70407

    1-5-Anhydroglucitol-6-phosphate dehydrogenase, escherichia coli

    Endogenous Metabolite Metabolic Disease
    Sorbitol-6-phosphate 2-dehydrogenase, escherichia coli is a dehydrogenase produced by E. coli. Sorbitol-6-phosphate 2-dehydrogenase, escherichia coli can catalyze the conversion between D-sorbitol 6-phosphate and D-fructose 6-phosphate, with the oxidation of D-sorbitol 6-phosphate happening at a rate 10 times faster than the reduction of D-fructose 6-phosphate, and it plays a role in various cellular processes .
    Sorbitol-6-phosphate 2-dehydrogenase, escherichia coli
  • HY-50289R

    Aldose Reductase Metabolic Disease
    Sorbinil (Standard) is the analytical standard of Sorbinil. This product is intended for research and analytical applications. Sorbinil is an aldose reductase inhibitor (ARI) that prevents the accumulation of sorbitol in cells or animals. Sorbinil is useful in studying diabetes and diabetic complications, reducing AR activity and inhibiting the polyol pathway .
    Sorbinil (Standard)
  • HY-105485

    Aldose Reductase Neurological Disease Metabolic Disease
    FR-62765 is a derivative of WF-3681. FR-62765 can significantly inhibit the accumulation of sorbitol in the sciatic nerve and the decrease of motor nerve conduction velocity in the tail of diabetic neuropathy rats, which can be used in the research of diabetic neuropathy .
    FR-62765
  • HY-W715538

    Aldose Reductase Metabolic Disease
    Rhetsinine is an aldose reductase inhibitor isolated from Evodia rutaecarpa, exhibiting an IC50 value of 24.1 μM. At a concentration of 100 μM, rhetsinine significantly inhibits sorbitol accumulation by 79.3%. This compound shows potential for research in diabetic complications, including diabetic neuropathy and retinopathy .
    Rhetsinine
  • HY-B0342R

    Methylglucamine (Standard); Meglumin (Standard); Methylglucamin (Standard)

    Biochemical Assay Reagents Reference Standards Cancer
    Meglumine (Standard) is the analytical standard of Meglumine. This product is intended for research and analytical applications. Meglumine (Methylglucamine) is an orally active amino sugar derived from sorbitol. Meglumine has anti-inflammatory and antitumor activity. Meglumine is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide .
    Meglumine (Standard)
  • HY-B0342GL

    Methylglucamine (GMP Like); Meglumin (GMP Like); Methylglucamin (GMP Like)

    Biochemical Assay Reagents Cancer
    Meglumine (GMP Like) (Methylglucamine (GMP Like)) is the GMP Like class Meglumine (HY-B0342) that can be used as pharmaceutical excipients. Meglumine (Methylglucamine) is an orally active amino sugar derived from sorbitol. Meglumine has anti-inflammatory and antitumor activity. Meglumine is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide .
    Meglumine (GMP Like)
  • HY-E70398A

    Endogenous Metabolite Metabolic Disease
    Sorbitol dehydrogenase, Sheep (EC 1.1.1.14) is an enzyme in carbohydrate metabolism that converts sorbitol, the sugar alcohol form of glucose, into fructose. Sorbitol dehydrogenase works in conjunction with aldose reductase, enabling the body to utilize glucose to produce fructose without ATP consumption. Sorbitol dehydrogenase uses NAD+ as a cofactor, and zinc ions also participate in the catalytic process.
    Sorbitol Dehydrogenase, Sheep
  • HY-149254

    Phosphatase Aldose Reductase Metabolic Disease
    PTP1B/AKR1B1-IN-1 is a dual inhibitor of protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AKR1B1), with IC50s of 0.06 μM and 4.3 μM, respectively. PTP1B/AKR1B1-IN-1 also inhibits TC-PTP with an IC50 value of 9 μM. PTP1B/AKR1B1-IN-1 serves as an insulin-mimetic agent in murine myoblasts, and reduces AKR1B1-dependent sorbitol accumulation. PTP1B/AKR1B1-IN-1 inhibits development of type 2 diabetes mellitus (T2DM) to control blood glucose levels .
    PTP1B/AKR1B1-IN-1
  • HY-106697R

    ICI 128436 (Standard)

    Reference Standards Aldose Reductase Metabolic Disease
    Ponalrestat (Standard) (ICI 128436 (Standard)) is the analytical standard of Ponalrestat (HY-106697). This product is intended for research and analytical applications. Ponalrestat (ICI 128436) is an orally active, selective and noncompetitive aldose reductase (AKR1B1; ALR) inhibitor. Ponalrestat selectively inhibits ALR2 (Ki=7.7 nM) over ALR1 (Ki=60 μM). Ponalrestat inhibits the conversion of glucose to sorbitol .
    Ponalrestat (Standard)
  • HY-N15464

    Aldehyde Dehydrogenase (ALDH) Metabolic Disease
    Antihepatotoxic agent-1 is a cerebroside present in Lycium chinense Fruits with antihepatotoxic activity. Antihepatotoxic agent-1 exerts a protective effect by blocking the release of alanine aminotransferase and sorbitol dehydrogenase from primary cultured rat hepatocytes intoxicated with carbon tetrachloride. Antihepatotoxic agent-1 can be used in studies related to liver injury .
    Antihepatotoxic agent-1
  • HY-N13152

    Others Others
    Dihydrotrichotetronine is a sorbitol compound .
    Dihydrotrichotetronine
  • HY-119058

    CP-744809

    Aldose Reductase Metabolic Disease
    ARI-809 (CP-744809) is a highly selective, orally active aldose reductase inhibitor with an IC50 of 1 nM. ARI-809 blocks excessive glucose flux through the polyol pathway. ARI-809 normalizes elevated sorbitol and fructose levels in sciatic nerve tissues of diabetic rat models, inhibits sorbitol accumulation in lens tissues, and brings elevated urinary albumin excretion close to normal. ARI-809 can be used in diabetes research .
    ARI-809
  • HY-183923

    Aldose Reductase Metabolic Disease Inflammation/Immunology
    SX 3202 is an aldose reductase inhibitor. SX 3202 can be used for the research of diabetic complications .
    SX 3202

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