8 Results for "

Sprague-Dawleys rat

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "Sprague-Dawleys rat" in MCE Product Catalog:

Cat. No.: HY-E70558
Target:  

5 alpha Reductase

Research Areas:  

Metabolic Disease

5α-reductase, Rat (Sprague-Dawley) Liver is an enzyme involved in steroid metabolism and participates in the androgen metabolic pathway. 5α-reductase, Rat (Sprague-Dawley) Liver catalyzes the conversion of testosterone to 5α-dihydrotestosterone (DHT). DHT plays important roles in the development of male sex organs, hair growth, prostate function, and other aspects .
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Cat. No.: HY-E70558A
Target:  

5 alpha Reductase

Research Areas:  

Endocrinology

5α-Reductase, Rat (Sprague-Dawley) Testis is the enzyme responsible for the conversion of testosterone into 5-alpha dihydrotestosterone (DHT), which is a potent androgen involved in male sexual differentiation.5α-reductase enzyme family is comprised of 3 subfamilies and 5 isoenzyme members: 5αR1, 5αR2, 5αR3, GPSN2, and GPSN2L .
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Cat. No.: HY-100801A
CAS No.: 4294-45-5
Purity:  99.77%
Target:  

Inhibitory Antibodies

Research Areas:  

Others

DL-threo-3-Hydroxyaspartic acid is a glutamate uptake inhibitor that can block glutamate transport in cannulated sprague dawley rat .
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Cat. No.: HY-N2196
CAS No.: 23044-80-6
Ajugasterone C is an ecdysteroid isolated from Leuzea carthamoides. Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to Carrageenan-induced inflammation in Sprague Dawley rats .
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Cat. No.: HY-124393
CAS No.: 1253291-12-1
Target:  

mGluR

Research Areas:  

Neurological Disease

GRN-529 is a negative allosteric modulator (NAM) for mGluR5. GRN-259 modulates sleep-wake activity, and exhibits anxiolytic efficacy in rats .
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Cat. No.: HY-N11925
CAS No.: 112923-64-5
(+)-Osbeckic acid is a vasorelaxatant that can be isolated from Tartary Buckwheat. (+)-Osbeckic acid has a potent vasorelaxant effect in Sprague-Dawley rat thoracic aorta rings with an EC50 of 887 μM .
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Cat. No.: HY-P5130
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

Big endothelin-1 (rat 1-39) is a 39-residues peptide. Big endothelin-1 (rat 1-39) induces diuretic and natriuretic response in conscious Sprague-Dawley rats. Big endothelin-1 (rat 1-39) raises blood pressure in mice .
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Cat. No.: HY-151360
CAS No.: 543734-50-5
Target:  

Sodium Channel

Research Areas:  

Metabolic Disease

NHE3-IN-3 (Compound 1) is a Na +/H + exchanger isoform 3 (NHE3) inhibitor with pIC50 of 6.2 and 6.6 against human and rat NHE3, respectively. NHE3-IN-3 shows high (98%) oral bioavailability in Sprague–Dawley rats .
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