Ajugasterone C
Based on 1 Customer Validation
Ajugasterone C is an ecdysteroid isolated from Leuzea carthamoides. Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to Carrageenan-induced inflammation in Sprague Dawley rats.
For research use only. We do not sell to patients.
- Purity: 98.31%
- CAS No.: 23044-80-6
- Formula: C27H44O7
- Molecular Weight:480.63
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
>700 μM
Compound: 3
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Cytotoxicity against human HuH7 cells assessed as reduction in cell viability after 72 hrs by MTS assay
Cytotoxicity against human HuH7 cells assessed as reduction in cell viability after 72 hrs by MTS assay
|
[PMID: 26988299] |
| Huh-7 | EC50 |
10.05 μM
Compound: 3
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Antiviral activity against Dengue virus 2 DN454009A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
Antiviral activity against Dengue virus 2 DN454009A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
|
[PMID: 26988299] |
| Huh-7 | EC50 |
12.15 μM
Compound: 3
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Antiviral activity against Dengue virus 4 S9201818 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
Antiviral activity against Dengue virus 4 S9201818 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
|
[PMID: 26988299] |
| Huh-7 | EC50 |
15.7 μM
Compound: 3
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Antiviral activity against Dengue virus 1 DN8700828 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
Antiviral activity against Dengue virus 1 DN8700828 infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
|
[PMID: 26988299] |
| Huh-7 | EC50 |
9.48 μM
Compound: 3
|
Antiviral activity against Dengue virus 3 DN8700829A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
Antiviral activity against Dengue virus 3 DN8700829A infected in human HuH7 cells assessed as inhibition of viral RNA level measured 72 hrs post infection by qRT-PCR method
|
[PMID: 26988299] |
Chemical Information
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CAS No. 23044-80-6
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Appearance Solid
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Molecular Weight 480.63
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Formula C27H44O7
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Color White to off-white
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SMILES
O[C@]([C@@]1(C[C@H]2O)C)(CC[C@]1([H])[C@@](C)(O)[C@H](O)CCC(C)C)C([C@@]2([H])[C@@]3([C@@]4([H])C[C@@H](O)[C@@H](O)C3)C)=CC4=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Santagati NA, et al. Analysis of ecdysteroids by micellar electrokinetic chromatography with on-line preconcentration. J Chromatogr A. 2005 Jul 15;1081(1):77-86. [Content Brief]
[2]. Ochieng CO, et al. Phytoecdysteroids from the stem bark of Vitex doniana and their anti-inflammatory effects. Planta Med. 2013 Jan;79(1):52-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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