2. Metabolic Enzyme/Protease
  3. 5 alpha Reductase
  4. 5α-reductase, Rat(Sprague-Dawley) Liver

5α-reductase, Rat (Sprague-Dawley) Liver is an enzyme involved in steroid metabolism and participates in the androgen metabolic pathway. 5α-reductase, Rat (Sprague-Dawley) Liver catalyzes the conversion of testosterone to 5α-dihydrotestosterone (DHT). DHT plays important roles in the development of male sex organs, hair growth, prostate function, and other aspects.

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5α-reductase, Rat(Sprague-Dawley) Liver

5α-reductase, Rat(Sprague-Dawley) Liver Chemical Structure

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500 μL In-stock

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Other Forms of 5α-reductase, Rat(Sprague-Dawley) Liver:

5α-reductase, Rat(Sprague-Dawley) Liver Related Antibodies

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Description

5α-reductase, Rat (Sprague-Dawley) Liver is an enzyme involved in steroid metabolism and participates in the androgen metabolic pathway. 5α-reductase, Rat (Sprague-Dawley) Liver catalyzes the conversion of testosterone to 5α-dihydrotestosterone (DHT). DHT plays important roles in the development of male sex organs, hair growth, prostate function, and other aspects[1].
In Vitro

5α-reductase activity in adult female rat liver microsomes peaks at pH 5.5, has an apparent Km of ~2 μM for testosterone and ~200 μM for NADPH at pH 6.9, and shows no detectable reverse reaction (androstanolone to testosterone)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5α-reductase, Rat(Sprague-Dawley) Liver Related Antibodies
Appearance

Liquid

Color

Light yellow to light brown

SMILES

[5a-reductase, Rat(Sprague-Dawley) Liver]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

SDS (251 KB)

COA (243 KB)

Handling Instructions (2659 KB)
References
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5α-reductase, Rat(Sprague-Dawley) Liver Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5α-reductase, Rat(Sprague-Dawley) Liver5 alpha Reductase5α-reductasesodium deoxycholatep-chloromercuribenzoateandrostanediolsCuandrostanoloneRat(Sprague-Dawley)NADPHNADPtestosteroneInhibitorinhibitorinhibit

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5α-reductase, Rat(Sprague-Dawley) Liver
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