3 Results for "

THP-1 human monocyte-derived macrophages

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "THP-1 human monocyte-derived macrophages" in MCE Product Catalog:

Cat. No.: HY-D2919
CAS No.: 2177287-88-4
DMN-Tre is a conjugate of a solvatochromic fluorescent dye and trehalose. DMN-Tre takes advantage of the substrate promiscuity of the endogenous antigen 85 protein complex in mycobacteria to be metabolically integrated into the hydrophobic mycobacterial membrane. Once entering this hydrophobic environment, the linked DMN dye fluorescence is "turned on", enabling specific labeling . DMN-Tre can be used to reflect bacterial metabolic activity and support physiological studies of Mycobacterium tuberculosis .
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Cat. No.: HY-176497
CAS No.: 1713317-28-2
Synonyms: G297X
Target:  

Cytochrome P450

Research Areas:  

Metabolic Disease Cancer

GW273297X is a selective CYP27A1 inhibitor. GW273297X blocks 27-hydroxycholesterol biosynthesis and sterol product formation in human macrophages. GW273297X reduces cancer cells colonization by inhibiting pro-metastatic effects of 27-hydroxycholesterol. GW273297X can be used for the researches of cancer and metabolic disease, such as breast cancer .
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Cat. No.: HY-171692
CAS No.: 2780391-08-2
Research Areas:  

Infection

G3-YSD is a cGAS agonist. G3-YSD directly interacts with cGAS to enhance its enzymatic activity, promote the conversion of ATP and GTP into cGAMP, and trigger STING-dependent IFN-α/β secretion. G3-YSD acts as a viral mimic to replace actual viral DNA . G3-YSD is applicable to research related to long COVID and type 1 human immunodeficiency virus infection .
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