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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
TLR7 agonist 1
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "TLR7 agonist 1" in MCE Product Catalog:
Target:
Research Areas:
TLR7 agonist 1 is a selective TLR7 agonist with an LEC value of 90 nM. TLR7 agonist 1 activates downstream immune regulation and shows no activity against TLR8. TLR7 agonist 1 induces endogenous IFN-α production in mice .
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1 Cited Publications
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TLR7/8 agonist 1 dihydrochloride is a toll-like receptor TLR7/TLR8 dual-agonistic imidazoquinoline .
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1 Cited Publications
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TLR7/8 agonist 1 is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline.
Synonyms: 7-Allyl-8-oxoguanosine; RWJ 21757
Loxoribine (7-Allyl-8-oxoguanosine) is a guanosine analog with anti-viral and anti-tumor activities. Loxoribine is an orally bioavailable and selective Toll-like receptor (TLR) 7 agonist .
Cat. No.: HY-111358R
CAS No.: 2178156-33-5
Research Areas:
TLR7 agonist 1 (Standard) is the analytical standard of TLR7 agonist 1 (HY-111358). This product is intended for research and analytical applications. TLR7 agonist 1 is a potent, selective and oral TLR7 agonist with an IC50 of 90 nM.
Cat. No.: HY-184473
Research Areas:
NOD1/TLR7 agonist-1 is a dual NOD1 and TLR7 agonist. NOD1/TLR7 agonist-1 exhibits adjuvant effects in mouse vaccine models and induces increased ovalbumin-specific IgG titers. NOD1/TLR7 agonist-1 can be used for research on immune-related diseases .
Cat. No.: HY-139575
CAS No.: 1488364-57-3
Synonyms: DSP-0509
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Research Areas:
Guretolimod (DSP-0509) is a Toll-like receptor 7 (TLR7) agonist .
Cat. No.: HY-103698R
CAS No.: 1258457-59-8
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TLR7/8 agonist 1 (Standard) is the analytical standard of TLR7/8 agonist 1 (HY-103698). This product is intended for research and analytical applications. TLR7/8 agonist 1 is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline.
Cat. No.: HY-103698AR
CAS No.: 1620278-72-9
Research Areas:
TLR7/8 agonist 1 dihydrochloride (Standard) is the analytical standard of TLR7/8 agonist 1 dihydrochloride (HY-103698A). This product is intended for research and analytical applications. TLR7/8 agonist 1 dihydrochloride is a toll-like receptor TLR7/TLR8 dual-agonistic imidazoquinoline .
Cat. No.: HY-139575A
Purity: 98.67%
Synonyms: DSP-0509 hydrochloride
Target:
Guretolimod hydrochloride is a Toll-like receptor 7 (TLR7) agonist .
Cat. No.: HY-117573
CAS No.: 1438280-73-9
Research Areas:
1Z105 is an orally active TLR4/MD2 agonist, immunostimulant and vaccine adjuvant. 1Z105 activates NF-κB via the MyD88/TRIF pathway in a CD14-independent manner, with EC50 values of 0.63 µM and 0.77 µM for inducing IL-6 and IL-12 in mBMDCs, respectively. 1Z105 promotes dendritic cell maturation, antigen uptake and cross-presentation; when used alone, it induces Th2-IgG1, while combined with the TLR7 agonist 1V270, it synergistically induces balanced Th1/Th2 responses and provides low-reactogenic protection against homologous, heterologous and heterosubtypic influenza. 1Z105 prevents LPS (HY-D1056A1)- and galactosamine-induced liver injury as well as autoantibody-driven arthritis in mice. 1Z105 can be used in studies related to influenza virus infection, inflammation, and LPS/galactosamine-induced liver injury .
Cat. No.: HY-108472R
CAS No.: 121288-39-9
Synonyms: 7-Allyl-8-oxoguanosine (Standard); RWJ 21757 (Standard)
Loxoribine (Standard) is the analytical standard of Loxoribine. This product is intended for research and analytical applications. Loxoribine (7-Allyl-8-oxoguanosine) is a guanosine analog with anti-viral and anti-tumor activities. Loxoribine is an orally bioavailable and selective Toll-like receptor (TLR) 7 agonist .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
