1438280-73-9
1438280-73-9
Chemical Structure
1Z105
- CAS No.: 1438280-73-9
- Formula:C25H26N4O2S
- Molecular Weight:446.56
IUPAC Name: N-cyclohexyl-2-((5-methyl-4-oxo-3-phenyl-4,5-dihydro-3H-pyrimido[5,4-b]indol-2-yl)thio)acetamide
InChIKey: XIGDXFCDNWREER-UHFFFAOYSA-N
SMILES: O=C1C2=C(C3=C(N2C)C=CC=C3)N=C(N1C4=CC=CC=C4)SCC(NC5CCCCC5)=O
Biological Activity: 1Z105 is an oral active TLR4/MD2 ligand. 1Z105 enhances dendritic cell maturation and antigen presentation and prevents rthritis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
1Z105 | 99.83% | 1Z105 is an oral active TLR4/MD2 ligand. 1Z105 enhances dendritic cell maturation and antigen presentation and prevents rthritis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Goff PH, et al. Synthetic Toll-like receptor 4 (TLR4) and TLR7 ligands as influenza virus vaccine adjuvants induce rapid, sustained, and broadly protective responses. J Virol. 2015;89(6):3221-3235. [Content Brief]
- [2]. Hayashi T, et al. Novel synthetic toll-like receptor 4/MD2 ligands attenuate sterile inflammation. J Pharmacol Exp Ther. 2014;350(2):330-340. [Content Brief]
Keywords
