2178156-33-5
2178156-33-5
Chemical Structure
TLR7 agonist 1
- CAS No.: 2178156-33-5
- Formula:C21H25N5O
- Molecular Weight:363.46
IUPAC Name: (S)-2-amino-4-(butylamino)-N-(1-phenylethyl)quinazoline-5-carboxamide
InChIKey: WDFAZLUMAXOURM-AWEZNQCLSA-N
SMILES: NC1=NC2=C(C(C(N[C@@H](C)C3=CC=CC=C3)=O)=CC=C2)C(NCCCC)=N1
Biological Activity: TLR7 agonist 1 is a selective TLR7 agonist with an LEC value of 90 nM. TLR7 agonist 1 activates downstream immune regulation and shows no activity against TLR8. TLR7 agonist 1 induces endogenous IFN-α production in mice[1].
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TLR7 agonist 1 | 98.19% | TLR7 agonist 1 is a selective TLR7 agonist with an LEC value of 90 nM. TLR7 agonist 1 activates downstream immune regulation and shows no activity against TLR8. TLR7 agonist 1 induces endogenous IFN-α production in mice. | ||||||||||||||||||||
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TLR7 agonist 1 (Standard) | ≥98% | TLR7 agonist 1 (Standard) is the analytical standard of TLR7 agonist 1 (HY-111358). This product is intended for research and analytical applications. TLR7 agonist 1 is a potent, selective and oral TLR7 agonist with an IC50 of 90 nM. | ||||||||||||||||||||
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