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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Transthyretin-IN-1
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Transthyretin-IN-1" in MCE Product Catalog:
Cat. No.: HY-146137
CAS No.: 3086836-18-9
Target:
Research Areas:
Transthyretin-IN-1 (Compound 1d) is a transthyretin (TTR) fibril formation inhibitor. Transthyretin-IN-1 can be used for Alzheimer’s disease research [1].
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4 Cited Publications
Target:
Research Areas:
PEG2000-C-DMG, a pegylated lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3′ untranslated region of transthyretin mRNA .
Synonyms: AG10
Target:
Research Areas:
Acoramidis (AG10) is an orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin). Acoramidis (AG10) is used in the study for transthyretin amyloidosis .
Synonyms: AG10 hydrochloride
Target:
Research Areas:
Acoramidis (AG10) hydrochloride is an orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin). Acoramidis (AG10) hydrochloride is used in the study for transthyretin amyloidosis .
Cat. No.: HY-185504
Nexiguran is one component of Nexiguran ziclumeran and also an sgRNA targeting the human TTR gene. Nexiguran ziclumeran (NTLA-2001) is a CRISPR gene-editing therapy that targets hepatic TTR, and it can also be used for research on transthyretin amyloidosis .
Cat. No.: HY-109165AR
CAS No.: 2242751-53-5
Synonyms: AG10 hydrochloride (Standard)
Research Areas:
Acoramidis hydrochloride (Standard) is the analytical standard of Acoramidis (hydrochloride) (HY-109165A). This product is intended for research and analytical applications. Acoramidis (AG10) hydrochloride is an orally active and selective Kinetic stabilizer of WT and V122I-TTR (transthyretin). Acoramidis (AG10) hydrochloride is used in the study for transthyretin amyloidosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
