1443687-74-8
1443687-74-8
Chemical Structure
PEG2000-C-DMG
- CAS No.: 1443687-74-8
- Formula:C126H249NO52
- Molecular Weight:2610.29
IUPAC Name: 1-heptyl-6,8-dihydroxyisochroman-3-one
SMILES: CCCCCCCCCCCCCC(O[C@@H](COC(NCCCOCCOC)=O)COC(CCCCCCCCCCCCC)=O)=O.[45]
Biological Activity: PEG2000-C-DMG, a pegylated lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3′ untranslated region of transthyretin mRNA[1][2].
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PEG2000-C-DMG | 99.97% | PEG2000-C-DMG, a pegylated lipid, can be used for the preparation of Onpattro. Onpattro, a hepatically directed investigational RNAi therapeutic agent, harnesses this process to reduce the production of mutant and wild-type transthyretin by targeting the 3′ untranslated region of transthyretin mRNA. | ||||||||||||||||||||
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PEG5000-C-DMG | PEG5000-C-DMG is a PEGylated derivative of 1,2-Dimyristoyl-sn-glycerol (HY-128468). PEG5000-C-DMG can be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of siRNA. | |||||||||||||||||||||
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PEG(2000)-C-DMG | 98.0% | PEG(2000)-C-DMG is a PEGylated derivative of 1,2-Dimyristoyl-sn-glycerol (HY-128468). PEG(2000)-C-DMG can be used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of siRNA. | ||||||||||||||||||||
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