PEG(2000)-C-DMG
Based on 1 Customer Validation
PEG(2000)-C-DMG is a PEGylated derivative of 1,2-Dimyristoyl-sn-glycerol (HY-128468). PEG(2000)-C-DMG can be used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of siRNA.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 1443687-74-8
- Molecular Weight:2600 (Approximately)
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
PEG(2000)-C-DMG can be used to prepare synthetic lipid nanoparticles for research on drug delivery[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 1443687-74-8
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Appearance Solid
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Molecular Weight 2600 (Approximately)
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Color White to off-white
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SMILES
CCCCCCCCCCCCCC(OC(COC(NCCCOCCOC)=O)COC(CCCCCCCCCCCCC)=O)=O.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : 50 mg/mL (Need ultrasonic)
Protocols
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RNA interference technology
RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing gene transcription or activating RNA degradation. This mechanism was discovered in plants in 1998 by Andrew Fire and Craig Mello. Today, this phenomenon can be observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals.
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)